3-(2-甲基苯基)丙酸乙酯合成路线 （共 17 条）
反应条件
N,N-dicyclohexylmethylamine; 4-hydroxyacetophenone oxime-derived palladacycle catalyst in N,N-dimethyl acetamide; water T=90°C; Heck coupling; 6 h;
参考文献
Najera, Carmen; Botella, Luis
Tetrahedron, 2005 , vol. 61, # 41 p. 9688 - 9695
反应条件
bis (triortho-tolylphosphine)palladium(II) chloride in tetrahydrofuran Ambient temperature;
参考文献
Nakamura, Eiichi; Aoki, Satoshi; Sekiya, Kouichi; Oshino, Hiroji; Kuwajima, Isao
Journal of the American Chemical Society, 1987 , vol. 109, # 26 p. 8056 - 8066
反应条件
bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl acetamide; benzene T=60°C; 1 h;
参考文献
Tamaru, Y.; Ochiai, H.; Nakamura, T.; Yoshida, Z.
Tetrahedron Letters, 1986 , vol. 27, # 8 p. 955 - 958
反应条件
1,2-bis(di-tert-butylphosphino)benzene; methanesulfonic acid; palladium diacetate in toluene P=4560 Torr; 12 h; Heating; Title compound not separated from byproducts;
参考文献
Yamamoto, Yoshikazu; Koizumi, Toru; Katagiri, Kosuke; Furuya, Yui; Danjo, Hiroshi; Imamoto, Tsuneo; Yamaguchi, Kentaro
Organic Letters, 2006 , vol. 8, # 26 p. 6103 - 6106
反应条件
pyrrolidine; potassium hydroxide; tris(triphenylphosphine)ruthenium(II) chloride; isopropyl alcohol in toluene 24 h; Inert atmosphereReflux;
参考文献
Pridmore, Simon J.; Williams, Jonathan M.J.
Tetrahedron Letters, 2008 , vol. 49, # 52 p. 7413 - 7415
反应条件
potassium carbonate; Pd-Tedicyp catalyst in N,N-dimethyl-formamide T=110°C; Heck reaction; 20 h;
参考文献
Lemhadri, Mhamed; Doucet, Henri; Santelli, Maurice
Tetrahedron, 2004 , vol. 60, # 50 p. 11533 - 11540
反应条件
1: HCl / diethyl ether / Heating 2: H2 / PtO2 / ethanol View Scheme
参考文献
Orr; Musso; Boswell; Kelley; Joyner; Davis; Baccanari
Journal of Medicinal Chemistry, 1995 , vol. 38, # 19 p. 3850 - 3856
反应条件
1: bromination 2: 83 percent / PdCl2(o-Tol3P)2 / tetrahydrofuran / Ambient temperature View Scheme
参考文献
Nakamura, Eiichi; Aoki, Satoshi; Sekiya, Kouichi; Oshino, Hiroji; Kuwajima, Isao
Journal of the American Chemical Society, 1987 , vol. 109, # 26 p. 8056 - 8066
反应条件
zinc(II) chloride; bis (triortho-tolylphosphine)palladium(II) chloride 1.) ether, vac., room temp.; 2.) THF, room temp.; Yield given. Multistep reaction;
参考文献
Nakamura, Eiichi; Kuwajima, Isao
Tetrahedron Letters, 1986 , vol. 27, # 1 p. 83 - 86
反应条件
potassium carbonate in ethanol; acetonitrile; tert-butyl alcohol Heck reaction;
参考文献
Martins, Daniela De L.; Alvarez, Heiddy M.; Aguiar, Lucia C.S.; Antunes, Octavio A.C.
Applied Catalysis A: General, 2011 , vol. 408, # 1-2 p. 47 - 53
