2-溴-1-(5-溴噻吩)-2-乙酮合成路线 （共 8 条）
反应条件
AlCl3, aluminium chloride; bromine in tetrahydrofuran T=0°C;
参考文献
Ostrowski, Tomasz; Golankiewicz, Bozenna; De Clercq, Erik; Andrei, Graciela; Snoeck, Robert
European Journal of Medicinal Chemistry, 2009 , vol. 44, # 8 p. 3313 - 3317
反应条件
bromine in 1,4-dioxane; dichloromethane
反应条件
hydrogen bromide; oxygen in water; ethyl acetate T=20°C; 24 h; Irradiation;
参考文献
Tada, Norihiro; Ban, Kazunori; Hirashima, Shin-Ichi; Miura, Tsuyoshi; Itoh, Akichika
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 20 p. 4701 - 4704
反应条件
AlCl3, aluminium chloride in carbon disulfide T=20°C; Friedel Crafts acylation; Reflux;
参考文献
Perez, Daniel I.; Conde, Santiago; Perez, Concepcion; Gil, Carmen; Simon, Diana; Wandosell, Francisco; Moreno, Francisco J.; Gelpi, Jose L.; Luque, Francisco J.; Martinez, Ana
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 19 p. 6914 - 6925
反应条件
Oxonereg;; sodium bromide in methanol; water 14 h; Heating;
参考文献
Synthetic Communications, , vol. 31, # 23 p. 3627 - 3632
反应条件
1-methyl-1H-imidazole in water; isopropyl alcohol T=20°C; 1.5 h;
参考文献
Meshram; Thakur, Pramod B.; Madhu Babu; Bangade, Vikas M.
Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5265 - 5269
反应条件
in acetone 0.5 h; Heating;
参考文献
Smirnov, V. A.; Zimichev, A. V.; Lyzhova, G. A.; Lipkin, A. E.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982 , vol. 18, # 1 p. 28 - 31
Khimiya Geterotsiklicheskikh Soedinenii, 1982 , vol. 18, # 1 p. 35 - 38
反应条件
in ethanol; water T=0 - 20°C;
参考文献
Baraldi, Pier Giovanni; Pavani, Maria Giovanna; Shryock, John C.; Moorman, Allan R.; Iannotta, Valeria; Borea, Pier Andrea; Romagnoli, Romeo
European Journal of Medicinal Chemistry, 2004 , vol. 39, # 10 p. 855 - 865
