反应条件
1: 76 percent / iron powder, bromine / CHCl3 / 48 h / Ambient temperature 2: 1.) NaOMe, CuCN / 1.) methanol, DME, dimethyl carbonate, 80 deg C, 5 h 2.) methanol, DME, water, RT, 2 h 3: 84 percent / pyridine-2,6-dicarboxylate, ceric ammonium nitrate (CAN) / acetonitrile; H2O / a.) 20 min, 0 deg C b.) 10 min, RT View Scheme
参考文献
Keinan, Ehud; Eren, Doron
Journal of Organic Chemistry, 1987 , vol. 52, # 17 p. 3872 - 3875
