(S)-2,6-二氨基-4,5,6,7-四氢苯并噻唑合成路线 （共 13 条）
反应条件
potassium carbonate in isopropyl alcohol T=80 - 82°C; 10.25 h;
参考文献
CADILA HEALTHCARE LIMITED
Patent: WO2008/41240 A1, 2008 ;
Location in patent: Page/Page column 18 ;
反应条件
1: 90 percent / triethylamine / tetrahydrofuran / 2 h / -5 °C 2: borane-tetrahydrofuran complex / tetrahydrofuran / 1 h / 50 °C View Scheme
参考文献
MSN LABORATORIES LIMITED; SATYANARAYANA REDDY, Manne; ESWARAIAH, Sajja; SAHADEVA REDDY, Maramreddy
Patent: WO2011/21214 A2, 2011 ;
反应条件
triethylamine in tetrahydrofuran T=-5°C; 2 h;
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 3 p. 494 - 498
