4-溴吡唑并[1,5-a]吡啶-3-羧酸甲酯合成路线 （共 2 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide 24 h;
参考文献
Cuny, Gregory D.; Yu, Paul B.; Laha, Joydev K.; Xing, Xuechao; Liu, Ji-Feng; Lai, Carol S.; Deng, Donna Y.; Sachidanandan, Chetana; Bloch, Kenneth D.; Peterson, Randall T.
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 15 p. 4388 - 4392
反应条件
1.1: hydroxylamine-o-sulphonic acid / water / 0.5 h / 90 °C 1.2: 20 °C 2.1: potassium carbonate / N,N-dimethyl-formamide / 24 h View Scheme
参考文献
MERZ PHARMA GMBH and CO. KGAA; HENRICH, Markus; WEIL, Tanja; HECHENBERGER, Mirko; MUeLLER, Sibylle; KAUSS, Valerjans; ZEMRIBO, Ronalds; ERDMANE, Elina; SMITS, Gints
Patent: WO2011/15343 A1, 2011 ;
WO 2011/015343 A1
