1: ethyl acetylene With ethyl bromide; magnesium in tetrahydrofuran T=20 - 30°C; 0.75 h; Cooling with ice; 2: formaldehyd in tetrahydrofuran T=20°C; 3 h; Reflux; 3: With sulfuric acid in water Cooling with ice;
参考文献
RETROTOPE, INC.
Patent: US2011/105609 A1, 2011 ;
Location in patent: Page/Page column 19 ;
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide in diethylamine T=40°C; 3 h;
参考文献
Mavrov, M. V.; Chrelashvili, Z. G.; Serebryakov, E. P.
Russian Chemical Bulletin, 1993 , vol. 42, # 4 p. 737 - 741
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1993 , # 4 p. 769 - 772
Mavrov, M. V.; Chrelashvili, Z. G.; Serebryakov, E. P.
Russian Chemical Bulletin, 1993 , vol. 42, # 4 p. 737 - 741
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1993 , # 4 p. 769 - 772
