6-氯-6-氧代己酸乙酯合成路线 （共 76 条）
反应条件
1: aluminium chloride; 1.1.2.2-tetrachloro-ethane / Behandeln des Reaktionsprodukts mit aethanol. bzw. wss. Natronlauge 2: ethanol; amalgamated zinc; aqueous hydrochloric acid 3: aqueous hydrobromic acid; acetic acid View Scheme
参考文献
Papa; Schwenk; Hankin
Journal of the American Chemical Society, 1947 , vol. 69, p. 3018,3021
反应条件
1: dry ammonia gas 2: 83 percent / tetrafluorophthalic anhydride / 60 h / 135 °C View Scheme
参考文献
Eaton, Jefferson T.; Rounds, William D.; Urbanowicz, John H.; Gribble, Gordon W.
Tetrahedron Letters, 1988 , vol. 29, # 50 p. 6553 - 6556
反应条件
aluminium trichloride; nitrobenzene Hydrolyse des Reaktionsprodukts;
参考文献
Fieser; Szmuszkovicz
Journal of the American Chemical Society, 1948 , vol. 70, p. 3352,3354
反应条件
1: (i) Mg, Et2O, (ii) CdCl2, (iii) /BRN= 1100317/, benzene 2: (i) Zn-Hg, aq. HCl, (ii) EtOH, HCl 3: H2 / CuO*Cr2O3 / 250 - 255 °C / 147102 Torr 4: PBr3 5: (i) Mg, Et2O, (ii) CdCl2, (iii) /BRN= 1100317/, benzene 6: (i) Zn-Hg, aq. HCl, (ii) KOH, EtOH 7: CrO3 / acetic acid / 100 °C View Scheme
参考文献
Nenitzesco,C.D.; Glatz,A.M.
Bulletin de la Societe Chimique de France, 1961 , p. 218 - 222
反应条件
1: benzene 2: aq. NaOH solution 3: potassium hydroxide; diethylene glycol; hydrazine hydrate / 200 °C View Scheme
参考文献
Kreuchunas
Journal of the American Chemical Society, 1953 , vol. 75, p. 3339,3342
反应条件
1: 76 percent / tin(IV) chloride / CH2Cl2 / 1.5 h / Ambient temperature 2: 91 percent / 95percent hydrazine hydrate, potassium hydroxide / ethane-1,2-diol / 4.5 h / 60 °C / Heating 3: 85 percent / Raney nickel-aluminium alloy / aq. NaOH / 3 h / 90 - 120 °C 4: 93 percent / lithium aluminium hydride / diethyl ether / 1.) RT, 1.5 h, 2.) reflux, 1h 5: 94 percent / 48percent hydrobromic acid, sulfuric acid / 24 h / Heating View Scheme
参考文献
Jefferson, Alan; Sargent, Melvyn V.; Wangchareontrakul, Sirichai
Australian Journal of Chemistry, 1988 , vol. 41, # 1 p. 19 - 25
反应条件
1: aluminium chloride; carbon disulfide 2: ethanolic NaOH-solution View Scheme
参考文献
Fieser et al.
Journal of the American Chemical Society, 1948 , vol. 70, p. 3177
反应条件
anschliessend Hydrolyse;
参考文献
Huisgen et al.
Chemische Berichte, 1957 , vol. 90, p. 1958,1965
反应条件
1: tin (IV)-chloride; carbon disulfide / Erwaermen des Reaktionsprodukts mit wss.-aethanol. Natronlauge 2: hydrazine hydrate; diethylene glycol / Erhitzen des mit Kaliumhydroxid versetzten Reaktionsgemisches bis auf 200grad 3: aq. NaOH solution; nickel-aluminium-alloy View Scheme
参考文献
Buu-Hoi et al.
Bulletin de la Societe Chimique de France, 1955 , p. 1583,1585
反应条件
aluminium trichloride; nitrobenzene Hydrolyse des Reaktionsprodukts;
参考文献
Fieser; Szmuszkovicz
Journal of the American Chemical Society, 1948 , vol. 70, p. 3352,3354
