3,5-二羟基-2-甲基-4H-吡喃-4-酮合成路线 （共 8 条）
反应条件
sulfuric acid
T=90 - 95°C;
参考文献
Takao, Hisashi; Endo, Yoshinori; Horie, Tokunaru
Heterocycles, 1992 , vol. 34, # 9 p. 1803 - 1812
反应条件
1: With piperidine in ethanol
Condensation; 2 h; Heating;
2: With mercaptoacetic acid in ethanol
Elimination; 24 h; Heating; Title compound not separated from byproducts;
参考文献
Cutzach, Isabelle; Chatonnet, Pascal; Henry, Robert; Dubourdieu, Denis
Journal of Agricultural and Food Chemistry, 1999 , vol. 47, # 4 p. 1663 - 1667
反应条件
1: 90 percent / 30percent aq. H2O2, 5percent aq. Na2CO3 / methanol / 2 h / 10 - 15 °C
2: 41 percent / 1percent aq. H2SO4 / 90 - 95 °C
View Scheme
参考文献
Takao, Hisashi; Endo, Yoshinori; Horie, Tokunaru
Heterocycles, 1992 , vol. 34, # 9 p. 1803 - 1812
反应条件
sodium hydroxide; sodium acetate; 2,6-diaminohexanoic acid hydrochloride in water
T=100°C; Condensation; Maillard reaction; Amadori rearrangement; P=750.06 Torr; pH=7; 5 h; Product distributionKinetics; Further Variations:ReagentspH-valuesPressures;
参考文献
Bristow, Mark; Isaacs, Neil S.
Journal of the Chemical Society. Perkin Transactions 2, 1999 , # 10 p. 2213 - 2218
参考文献
Kosuge; Tsuji; Nukaya; et al.
Agricultural and Biological Chemistry, 1983 , vol. 47, # 4 p. 881 - 883
反应条件
sulfuric acid
T=60 - 65°C; 6 h; other 4,5-epoxy-4-halo-6-methoxy-2-methyltetrahydropyran-3-one, var. acids, other time; Product distributionMechanism;
参考文献
Takao, Hisashi; Endo, Yoshinori; Horie, Tokunaru
Heterocycles, 1992 , vol. 34, # 9 p. 1803 - 1812
反应条件
water
T=150°C; 1 h; also 2,3-dihydro-3,5-dihydroxy-6(13C)methyl-4(H)-pyran-4-one; var. temp., pH, and time; effect of 2,4-dihydroxy-2,5-dimethyl-3(2H)-furanone;
参考文献
Kim, Myong-Ock; Baltes, Werner
Journal of Agricultural and Food Chemistry, 1996 , vol. 44, # 1 p. 282 - 289
反应条件
in water
T=95°C; 120 h; other reaction time, other temperature; Product distribution;
参考文献
Hayase, Fumikata; Kim, Bong Seon; Kato, Hiromichi
Agricultural and Biological Chemistry, 1985 , vol. 49, # 8 p. 2337 - 2342
