1,3,5-三甲基己羟基-1,3,5-三嗪合成路线 （共 63 条）
反应条件
zinc(II) chloride
T=130°C; 1 h; Inert atmosphere;
参考文献
Prishchenko, Andrey A.; Livantsov, Mikhail V.; Novikova, Olga P.; Livantsova, Ludmila I.; Petrosyan, Valery S.
Heteroatom Chemistry, 2010 , vol. 21, # 2 p. 71 - 77
反应条件
zinc(II) chloride
T=135°C; 1 h;
参考文献
Prishchenko, Andrey A.; Livantsov, Mikhail V.; Novikova, Olga P.; Livantsova, Ludmila I.; Petrosyan, Valery S.
Heteroatom Chemistry, 2008 , vol. 19, # 5 p. 495 - 499
反应条件
1: 1,3,5-trimethyl-hexahydro-1,3,5-triazine; formaldehyd; ethanol 1 h; Inert atmosphereReflux;
2: phosphonic acid diethyl ester 2 h; RefluxInert atmosphere;
参考文献
Prishchenko, Andrey A.; Livantsov, Mikhail V.; Novikova, Olga P.; Livantsova, Ludmila I.; Petrosyan, Valery S.
Heteroatom Chemistry, 2010 , vol. 21, # 6 p. 430 - 440
反应条件
in dichloromethane
Ambient temperatureovernight;
参考文献
Siver; Sloan
Journal of Pharmaceutical Sciences, 1990 , vol. 79, # 1 p. 66 - 73
反应条件
trifluoroacetic acid
T=100°C; 24 h;
参考文献
Darnbrough, Geoffrey; Knowles, Philip; O'Connor, Sean P.; Ttierney, Francis J.
Tetrahedron, 1986 , vol. 42, # 8 p. 2339 - 2344
反应条件
hydrogenchloride
T=225°C; 0.25 h; Mechanism;
参考文献
D'Silva, Themistocles D. J.; Lopes, Anibal
Journal of the Chemical Society, Chemical Communications, 1986 , # 10 p. 795 - 796
参考文献
Kostyuchenko, V. M.; Kiryukhina, G. A.
Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, # 10 p. 2052 - 2054
Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 10 p. 2243 - 2245
反应条件
chloro-trimethyl-silane in toluene; acetonitrile
Heating / reflux; Product distribution / selectivity;
参考文献
YUHAN CORPORATION
Patent: WO2005/37822 A1, 2005 ;
Location in patent: Page/Page column 11 ;
反应条件
phosphorus pentachloride in dichloromethane
T=40°C; 5 h;
参考文献
Sumitomo Chemical Takeda Agro Company, Limited
Patent: EP1481972 A1, 2004 ;
Location in patent: Page 26 ;
反应条件
1.) CHCl3, r.t., 1 h, 2.) CHCl3, reflux, 20 h; Yield given. Multistep reaction. Title compound not separated from byproducts;
参考文献
Ikeda, Kiyoshi; Morimoto, Toshiaki; Sekiya, Minoru
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 4 p. 1178 - 1182
