1: thiophenol With sodium carbonate in water T=20°C; 0.5 h; 2: β-chloro-L-alanine With sodium carbonate in water pH=8 - 10; 5 h; 3: With hydrogenchloride in water; toluene pH=0.5;
1: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 1 h / -78 °C / Inert atmosphere 2: hydrogenchloride / water / Reflux 3: methyloxirane / ethanol / 0.67 h / Reflux View Scheme
参考文献
Aydillo, Carlos; Avenoza, Alberto; Busto, Jesus H.; Jimenez-Oses, Gonzalo; Peregrina, Jesus M.; Zurbano, Maria M.
Organic Letters, 2012 , vol. 14, # 1 p. 334 - 337