n-butyllithium; diisopropylamine in tetrahydrofuran; hexane
T=-50°C; 1 h;
参考文献
Hulst, Ron; Muizebelt, Inouk; Oosting, Peter; Van Der Pol, Cornelia; Wagenaar, Anno; Smisterova, Jarmila; Bulten, Erna; Driessen, Cecile; Hoekstra, Dick; Engberts, Jan B. F. N.
European Journal of Organic Chemistry, 2004 , # 4 p. 835 - 849
1: With n-butyllithium; diisopropylamine
T=20°C; Cooling with ice/salt;
2: 3-Methylpyridine in toluene
T=0°C; 0.5 h;
3: 4-chlorobenzoic acid methyl ester With water
more than 3 stages;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2004/11410 A1, 2004 ;
Location in patent: Page 84 ;
WO 2004/011410 A1
