2-甲基哌嗪合成路线

2-甲基哌嗪合成路线（共 109 条）

参考文献

Bristol-Myers Squibb Company
Patent: US6469006 B1, 2002 ;

109-07-92-甲基哌嗪+

112811-72-01-环丙基-6,7-二氟-1,4-二氢-8-甲氧基-4-氧代-3-喹啉羧酸

160738-57-8盐酸加替沙星

参考文献

QUIMICA SINTETICA, S.A.
Patent: WO2005/47262 A1, 2005 ;
Location in patent: Page/Page column 7-8 ;

109-07-92-甲基哌嗪+

847233-56-1

160738-57-8盐酸加替沙星

参考文献

Sanchez, Joseph P.; Gogliotti, Rocco D.; Domagala, John M.; Gracheck, Stephen J.; Huband, Michael D.; et al.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 22 p. 4478 - 4487

24424-99-5二碳酸二叔丁酯+

109-07-92-甲基哌嗪+

501-53-1氯甲酸苄酯

128102-16-9(R)-1-Boc-4-Cbz-2-甲基哌嗪

参考文献

BIOMARIN PHARMACEUTICAL INC.; WANG, Bing; CHU, Daniel
Patent: WO2011/130661 A1, 2011 ;
Location in patent: Page/Page column 167 ;

24424-99-5二碳酸二叔丁酯+

109-07-92-甲基哌嗪

120737-59-91-Boc-3-甲基哌嗪

参考文献

Millennium Pharmaceuticals, Inc.
Patent: US2003/153556 A1, 2003 ;
US 20030153556 A1

109-07-92-甲基哌嗪+

91612-43-0

120737-59-91-Boc-3-甲基哌嗪

参考文献

DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1591443 A1, 2005 ;
Location in patent: Page/Page column 61 ;

109-07-92-甲基哌嗪+

73371-96-7

120737-59-91-Boc-3-甲基哌嗪

参考文献

DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1621537 A1, 2006 ;
Location in patent: Page/Page column 39-40 ;

58632-95-42-(叔丁氧羰基氧亚氨基)-2-苯乙腈+

109-07-92-甲基哌嗪

120737-59-91-Boc-3-甲基哌嗪

参考文献

Giardina, Dario; Gulini, Ugo; Massi, Maurizio; Piloni, Maria G.; Pompei, Pierluigi; et al.
Journal of Medicinal Chemistry, 1993 , vol. 36, # 6 p. 690 - 698

34619-03-9+

109-07-92-甲基哌嗪

120737-59-91-Boc-3-甲基哌嗪

参考文献

CHIRON CORPORATION
Patent: WO2004/18419 A2, 2004 ;
Location in patent: Page 339 ;

120737-59-91-Boc-3-甲基哌嗪

参考文献

Janssen Pharmaceutica N.V.
Patent: US4880808 A1, 1989 ;

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