3-吗啉酮合成路线

参考文献

PORTOLA PHARMACEUTICALS, INC.
Patent: WO2006/63293 A2, 2006 ;
Location in patent: Page/Page column 43 ;
WO 2006/063293 A2

109-11-53-吗啉酮+

106-40-1对溴苯胺

438056-69-04-(4-氨基苯基)吗啉-3-酮

参考文献

Al-Horani, Rami A.; Mehta, Akul Y.; Desai, Umesh R.
European Journal of Medicinal Chemistry, 2012 , vol. 54, p. 771 - 783

109-11-53-吗啉酮+

586-78-71-溴-4-硝基苯

446292-04-24-(3-氧代-4-吗啉基)硝基苯

参考文献

GALAPAGOS NV; MENET, Christel Jeanne Marie; BLANC, Javier; JOUANNIGOT, Nolwenn; HODGES, Alastair James; VAN ROMPAEY, Luc Juliaan Corina; FLETCHER, Stephen Robert
Patent: WO2010/10189 A1, 2010 ;
Location in patent: Page/Page column 55 ;
WO 2010/010189 A1

109-11-53-吗啉酮+

350-46-9对氟硝基苯

446292-04-24-(3-氧代-4-吗啉基)硝基苯

参考文献

Straub, Alexander; Lampe, Thomas; Pohlmann, Jens; Rohrig, Susanne; Perzborn, Elisabeth; Schlemmer, Karl-Heinz; Pernerstorfer, Joseph
Patent: US2003/153610 A1, 2003 ;

109-11-53-吗啉酮

21009-57-4

参考文献

WYETH
Patent: WO2003/93277 A1, 2003 ;
Location in patent: Page/Page column 93 ;

19172-47-5劳森试剂+

109-11-53-吗啉酮

21009-57-4

参考文献

Wyeth
Patent: US2004/132708 A1, 2004 ;

109-11-53-吗啉酮+

74-88-4甲基碘

20721-78-2

参考文献

Seguin; Vieles
Bulletin de la Societe Chimique de France, 1956 , p. 1210
Full Text Show Details
Vieles; Seguin
Bulletin de la Societe Chimique de France, 1953 , p. 287

109-11-53-吗啉酮+

29632-74-42-氟-4-碘苯胺

742073-22-9

参考文献

Bayers Schering Pharma Aktiengesellschaft
Patent: US2011/172232 A1, 2011 ;
Location in patent: Page/Page column 12 ;

109-11-53-吗啉酮+

368-39-8三乙基氧翁四氟硼酸

6578-40-1

参考文献

Glushkov,R.G.; Magidson,O.Yu.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1966 , vol. 2, p. 134 - 137
Khimiya Geterotsiklicheskikh Soedinenii, 1966 , vol. 2, p. 192 - 196

109-11-53-吗啉酮+

2576-47-82-溴乙胺氢溴酸盐

60928-27-0

参考文献

Rokach,J. et al.
Journal of Medicinal Chemistry, 1979 , vol. 22, p. 237 - 247