1-溴-3-氯丙烷合成路线

参考文献

ESPERION THERAPEUTICS, INC.
Patent: WO2005/68410 A1, 2005 ;
Location in patent: Page/Page column 239; 255-256 ;
WO 2005/068410 A1

110-89-4哌啶+

109-70-61-溴-3-氯丙烷

1458-63-5N-(3-氯丙基)哌啶

参考文献

Buchanan, John L.; Newcomb, John R.; Carney, David P.; Chaffee, Stuart C.; Chai, Lilly; Cupples, Rod; Epstein, Linda F.; Gallant, Paul; Gu, Yan; Harmange, Jean-Christophe; Hodge, Kathy; Houk, Brett E.; Huang, Xin; Jona, Janan; Joseph, Smriti; Jun, H. Toni; Kumar, Rakesh; Li, Chun; Lu, John; Menges, Tom; Morrison, Michael J.; Novak, Perry M.; Van Der Plas, Simon; Radinsky, Robert; Rose, Paul E.; Sawant, Satin; Sun, Ji-Rong; Surapaneni, Sekhar; Turci, Susan M.; Xu, Keyang; Yanez, Evelyn; Zhao, Huilin; Zhu, Xiaotian
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 8 p. 2394 - 2399

109-70-61-溴-3-氯丙烷+

263149-10-64-氯-7-羟基-6-甲氧基喹啉-3-甲腈

214470-68-54-氯-7-(3-氯-丙氧基)-6-甲氧基-喹啉-3-甲腈

参考文献

ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2004/5284 A1, 2004 ;
Location in patent: Page 80 ;
WO 2004/005284 A1

109-70-61-溴-3-氯丙烷+

352-13-6

64747-82-6

参考文献

UNIVERSITY OF PRINCE EDWARD ISLAND; GENESIS GROUP INC.; SHAVER, Michael, P.; KOZAK, Christopher, M.
Patent: WO2013/53046 A1, 2013 ;
Location in patent: Paragraph 00187-00191 ;

参考文献

Qian, Xin; Dawe, Louise N.; Kozak, Christopher M.
Dalton Transactions, 2011 , vol. 40, # 4 p. 933 - 943

1953-54-4+

109-70-61-溴-3-氯丙烷

70260-95-6

参考文献

Mahindroo, Neeraj; Wang, Chiung-Chiu; Liao, Chun-Chen; Huang, Chien-Fu; Lu, I.-Lin; Lien, Tzu-Wen; Peng, Yi-Huei; Huang, Wei-Jan; Lin, Ying-Ting; Hsu, Ming-Chen; Lin, Chia-Hui; Tsai, Chia-Hua; Hsu, John T.-A.; Chen, Xin; Lyu, Ping-Chiang; Chao, Yu-Sheng; Wu, Su-Ying; Hsieh, Hsing-Pang
Journal of Medicinal Chemistry, 2006 , vol. 49, # 3 p. 1212 - 1216

2380-86-1+

109-70-61-溴-3-氯丙烷

70260-96-7

参考文献

Mahindroo, Neeraj; Huang, Chien-Fu; Peng, Yi-Huei; Wang, Chiung-Chiu; Liao, Chun-Chen; Lien, Tzu-Wen; Chittimalla, Santhosh Kumar; Huang, Wei-Jan; Chai, Chia-Hua; Prakash, Ekambaranellore; Chen, Ching-Ping; Hsu, Tsu-An; Peng, Cheng-Hung; Lu, I-Lin; Lee, Ling-Hui; Chang, Yi-Wei; Chen, Wei-Cheng; Chou, Yu-Chen; Chen, Chiung-Tong; Goparaju, Chandra M. V.; Chen, Yuan-Shou; Lan, Shih-Jung; Yu, Ming-Chen; Chen, Xin; Chao, Yu-Sheng; Wu, Su-Ying; Hsieh, Hsing-Pang
Journal of Medicinal Chemistry, 2005 , vol. 48, # 26 p. 8194 - 8208

109-70-61-溴-3-氯丙烷+

110-60-1

70862-15-6

参考文献

Schwesinger, Reinhard; Willaredt, Juergen; Schlemper, Helmut; Keller, Manfred; Schmitt, Dieter; Fritz, Hans
Chemische Berichte, 1994 , vol. 127, # 12 p. 2435 - 2454

参考文献

Ciba-Geigy Corporation
Patent: US4197302 A1, 1980 ;

Title/Abstract Full Text Show Details
Ciba-Geigy Corporation
Patent: US4202901 A1, 1980 ;

参考文献

Warner-Lambert Company
Patent: US4665226 A1, 1987 ;