2,5-二甲基-2,5-己二醇合成路线 （共 107 条）
反应条件
1: 56 percent / HCl gas / ethanol 2: 54 percent / AlCl3 / hexane; CH2Cl2 / 1.) RT, 30 min, 2.) reflux, 15 min View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 37, # 18 p. 2930 - 2941
反应条件
aluminium trichloride; Petroleum ether
参考文献
US2198374 , ;
Journal of the American Chemical Society, , vol. 62, p. 36,43
参考文献
US2198374 , ;
Journal of the American Chemical Society, , vol. 62, p. 36,43
Chem.Abstr., , p. 5463
反应条件
1: aniline hydrobromide 2: AlCl3; petroleum ether View Scheme
参考文献
Bruson; Kroeger
Journal of the American Chemical Society, 1940 , vol. 62, p. 36,43
反应条件
1: HCl 2: AlCl3; petroleum ether / anschliessendes Erwaermen auf 95-100grad View Scheme
参考文献
Bruson; Kroeger
Journal of the American Chemical Society, 1940 , vol. 62, p. 36,43
反应条件
N-iodo-succinimide in benzene 0.916667 h; Irradiationvarying reaction time; Product distributionMechanism;
参考文献
Journal of Organic Chemistry, , vol. 49, # 20 p. 3843 - 3845
反应条件
1: 56 percent / HCl gas / ethanol 2: 90 percent / AlCl3 / CH2Cl2 / 1.) RT, 30 min, 2.) reflux, 15 min View Scheme
参考文献
Boehm; Zhang; Badea; White; Mais; Berger; Suto; Goldman; Heyman
Journal of Medicinal Chemistry, 1994 , vol. 37, # 18 p. 2930 - 2941
反应条件
1: 56 percent / HCl gas / ethanol 2: 92 percent / AlCl3 / hexane / 1.) RT, 30 min, 2.) reflux, 15 min View Scheme
参考文献
Guerrero Jr., Palimecio G.; De Oliveira, Paulo R.; Baroni, Adriano C.M.; Marques, Francisco A.; Labes, Ricardo; Hurtado, Gabriela R.; Dabdoub, Miguel J.
Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5302 - 5305
反应条件
1: HCl conc. / 3 h / 20 °C 2: 99 percent / AlCl3 / CH2Cl2 / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 17 p. 5772 - 5782
反应条件
1.1: hydrogenchloride / water / 20 °C 2.1: AlCl3, aluminium chloride / dichloromethane / |Reflux 3.1: palladium dichloride; copper(l) iodide; triethylamine / methanol / 20 °C / |Sonication 4.1: sodium hydride / toluene / |Reflux 4.2: 20 °C 5.1: n-butyllithium / tetrahydrofuran / -78 °C 5.2: 20 °C 6.1: tetrahydrofuran; hexane / 0.17 h / 0 - 20 °C / |Inert atmosphere 6.2: 2 h / |Reflux; |Inert atmosphere 7.1: tetrahydrofuran; hexane / 0.17 h / -78 °C / |Inert atmosphere 8.1: tetrahydrofuran; hexane / 0.5 h / |Inert atmosphere 9.1: Cl2Ni(1,2-bis(diphenylphosphino)ethane) / tetrahydrofuran / 5 h / |Inert atmosphere; |Reflux 10.1: water; hydrogenchloride / 3 h / |Reflux View Scheme
参考文献
Guerrero Jr., Palimecio G.; De Oliveira, Paulo R.; Baroni, Adriano C.M.; Marques, Francisco A.; Labes, Ricardo; Hurtado, Gabriela R.; Dabdoub, Miguel J.
Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5302 - 5305
