哌嗪合成路线 - 魔法化学

参考文献

Moltzen, Ejner K.; Kramer, Michael P.; Senning, Alexander; Klabunde, Kenneth J.
Journal of Organic Chemistry, 1987 , vol. 52, # 6 p. 1156 - 1161

110-85-0哌嗪+

103995-01-31-(2,4-二氟苯基)-6,7-二氟-1,4-二氢-4-氧代喹啉-3-羧酸

108138-27-8

参考文献

Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M.
Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

110-85-0哌嗪+

28948-58-57-氯噻吩并[2,3-c]吡啶

106261-29-4

参考文献

New, James S.; Christopher, William L.; Yevich, Joseph P.; Butler, Rhett; Schlemmer, R. Francis; et al.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 6 p. 1147 - 1156

110-85-0哌嗪+

34784-04-85-溴异喹啉

105685-17-45-哌嗪-1-基-异喹啉

参考文献

Fisher, Matthew J.; Backer, Ryan T.; Husain, Saba; Hsiung, Hansen M.; Mullaney, Jeffrey T.; O'Brian, Thomas P.; Ornstein, Paul L.; Rothhaar, Roger R.; Zgombick, John M.; Briner, Karin
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 20 p. 4459 - 4462

110-85-0哌嗪+

4521-61-33,4,5-三甲氧基苯甲酰氯

964-65-8+

1062-48-2

参考文献

Carceller; Almansa; Merlos; Giral; Bartroli; Garcia-Rafanell; Forn
Journal of Medicinal Chemistry, 1992 , vol. 35, # 22 p. 4118 - 4134

110-85-0哌嗪+

109577-76-6

109577-83-56-氯-N-(苯基甲基)-2-哌嗪-1-基-4-吡咯烷-1-基蝶啶-7-胺

参考文献

Merz, Karl-Heinz; Marko, Doris; Regiert, Thomas; Reiss, Guido; Frank, Walter; Eisenbrand, Gerhard
Journal of Medicinal Chemistry, 1998 , vol. 41, # 24 p. 4733 - 4743

110-85-0哌嗪+

42144-78-52-氯-6-乙氧基吡啶

108122-25-41-(6-乙氧基-2-哌啶)哌嗪

参考文献

Pavia, Michael R.; Taylor, Charles P.; Hershenson, Fred M.; Lobbestael, Sandra J.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 7 p. 1210 - 1214

110-85-0哌嗪+

36404-88-3

104842-73-1

参考文献

Bristol-Myers Company
Patent: US4619930 A1, 1986 ;
US 4619930 A
Title/Abstract Full Text Show Details
Bristol-Myers Company
Patent: US4757073 A1, 1988 ;
US 4757073 A

110-85-0哌嗪+

446-52-6

112253-19-7

参考文献

Keypour, Hassan; Rahpeyma, Nasibeh; Arzhangi, Parisa; Rezaeivala, Majid; Elerman, Yalcin; Buyukgungor, Orhan; Valencia, Laura
Polyhedron, 2010 , vol. 29, # 3 p. 1144 - 1148

110-85-0哌嗪+

103772-14-1

110236-78-7

参考文献

Domagala, John M.; Hagen, Susan E.; Heifetz, Carl L.; Hutt, Marland P.; Mich, Thomas F.; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, p. 503 - 506