1: 3-phenyl-2-propynoic acid With silver(l) oxide in N,N-dimethyl-formamide T=20°C; 0.0833333 h; Inert atmosphere; 2: 2-Iodo-benzoic acid ethyl ester With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; triphenylphosphine; lithium iodide in N,N-dimethyl-formamide T=70°C; Sonogashira coupling; 6 h; Inert atmosphere;

tris(dibenzylideneacetone)dipalladium(0) chloroform complex; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; silver(l) oxide; lithium iodide in N,N-dimethyl-formamide T=70°C; 2 h; Inert atmosphere;

bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine in tetrahydrofuran Addition;

copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride T=120°C; 6 h;

copper monoiodide in triethylamine

Parkins' catalyst T=78°C; 16 h; regioselective reaction;

1: 66 percent Spectr. / HBF4 / CH2Cl2; diethyl ether / 20 °C 2: 11 percent / NH3 / CH2Cl2 / 20 h View Scheme

tetrafluoroboric acid in diethyl ether; dichloromethane T=20°C; Cyclization;

sulfuric acid; mercuric sulphate in water; acetone 48 h; Heating;