2-(甲氧基甲氧基)-1,3-丙烷二基二苯甲酸酯合成路线 (共 4 条)
反应条件
1: benzoyl chloride; glycerol With triethylamine in chloroform T=20°C; Ice cooling; 2: dimethylformaldehyde dimethyl acetal With phosphorus pentoxide T=20°C;
参考文献
EP2128140 A1, ;
Page/Page column 7 ;
反应条件
15-crown-5 in N,N-dimethyl-formamide 48 h; Heating;
参考文献
Beauchamp, Lilia M.; Serling, Barbara L.; Kelsey, John E.; Biron, Karen K.; Collins, Peter; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 1 p. 144 - 149
反应条件
boron trifluoride diethyl etherate T=0°C; 2 h;
参考文献
Beauchamp, Lilia M.; Serling, Barbara L.; Kelsey, John E.; Biron, Karen K.; Collins, Peter; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 1 p. 144 - 149
反应条件
1: With boron trifluoride diethyl etherate T=20°C; 1 h; 2: With water; sodium carbonate
参考文献
Pola Pharma Inc.
Patent: EP2128140 A1, 2009 ;
Location in patent: Page/Page column 7 ;