反应条件
1.1: n-butyllithium / tetrahydrofuran; hexane / 1.5 h / -60 - 0 °C / Inert atmosphere
1.2: -60 - 20 °C / Inert atmosphere
2.1: N-bromosuccinmide / N,N-dimethyl-formamide / 20 °C / Darkness
3.1: magnesium / diethyl ether / 4 h / Inert atmosphere; Reflux
3.2: 48 h / Inert atmosphere; Reflux
4.1: N-bromosuccinmide / N,N-dimethyl-formamide / 20 °C / Darkness
View Scheme
参考文献
Shaik, Baji; Park, Ji Hee; An, Tae Kyu; Noh, Young Ri; Yoon, Soon Byung; Park, Chan Eon; Yoon, Young Jin; Kim, Yun-Hi; Lee, Sang-Gyeong
Tetrahedron, 2013 , vol. 69, # 38 p. 8191 - 8198