乙基3,3-二(二乙氧基磷酰)丙酸酯合成路线 （共 8 条）
反应条件
aluminum oxide; potassium hydroxide in dichloromethane T=20°C; 0.0833333 h;
参考文献
Semenzin, Delphine; Etemad-Moghadam, Guita; Albouy, Dominique; Diallo, Ousmane; Koenig, Max
Journal of Organic Chemistry, 1997 , vol. 62, # 8 p. 2414 - 2422
参考文献
Romanova, I. P.; Muslinkin, A. A.; Musin, R. Z.
J. Gen. Chem. USSR (Engl. Transl.), 1991 , vol. 61, # 12 p. 2698 - 2700,2504 - 2506
反应条件
1: NaH / toluene / 25 °C View Scheme
参考文献
Quimby,O.T. et al.
Journal of Organometallic Chemistry, 1968 , vol. 13, p. 199 - 207
反应条件
T=160 - 170°C; 10 h;
参考文献
Romanova, I. P.; Muslinkin, A. A.; Musin, R. Z.
J. Gen. Chem. USSR (Engl. Transl.), 1991 , vol. 61, # 12 p. 2698 - 2700,2504 - 2506
反应条件
sodium hydride 1.) THF, 10 deg C, 2.) THF, 90 min; Yield given. Multistep reaction;
参考文献
Guervenou, J.; Sturtz, G.
Phosphorus, Sulfur and Silicon and the Related Elements, 1994 , vol. 88, # 1-4 p. 1 - 14
参考文献
Quimby,O.T. et al.
Journal of Organometallic Chemistry, 1968 , vol. 13, p. 199 - 207
反应条件
aluminum oxide; triethylamine T=20°C; 0.333333 h; the role of base catalysts; Product distribution;
参考文献
Albouy, Dominique; Lasperas, Monique; Etemad-Moghadam, Guita; Koenig, Max
Tetrahedron Letters, 1999 , vol. 40, # 12 p. 2311 - 2314
反应条件
hydrogenchloride; sodium hydroxide in ethanol; water
参考文献
Zeneca Limited
Patent: US5728650 A1, 1998 ;
