Alpha-羟基-环己基甲酸合成路线 （共 62 条）
反应条件
hydrogenchloride in water 21 h; Reflux;
参考文献
Yosef; Elmasry; Ismael, Eman H. I.; Mahran
Egyptian Journal of Chemistry, 2010 , vol. 53, # 5 p. 745 - 755
反应条件
hydrogenchloride; water T=20 - 60°C; 2 h; Inert atmosphere;
参考文献
Maegawa, Tomohiro; Otake, Kazuki; Hirosawa, Keiichi; Goto, Akihiro; Fujioka, Hiromichi
Organic Letters, 2012 , vol. 14, # 18 p. 4798 - 4801
反应条件
1: hydrochloric acid; diethyl ether 2: fuming hydrochloric acid View Scheme
参考文献
Chemische Berichte, , vol. 27, p. 1231
反应条件
potassium hydroxide 1 h; Ambient temperature;
参考文献
Yabuuchi, Tetsuya; Kusumi, Takenori
Chemical and Pharmaceutical Bulletin, 1999 , vol. 47, # 5 p. 684 - 686
反应条件
potassium hydroxide; 18-crown-6 ether; water in dichloromethane T=20°C; 12 h;
参考文献
Synthetic Communications, , vol. 39, # 8 p. 1457 - 1471
反应条件
potassium hydroxide; 18-crown-6 ether; water in isopropyl alcohol T=20°C; 24 h;
参考文献
Synthetic Communications, , vol. 39, # 8 p. 1457 - 1471
反应条件
potassium hydroxide; 18-crown-6 ether; water in 1,1-dimethylpropan-1-ol T=20°C; 12 h;
参考文献
Synthetic Communications, , vol. 39, # 8 p. 1457 - 1471
反应条件
1: sodium acetate; dinitrogen tetraoxide / tetrachloromethane / 3 h / 0 °C 2: tetrachloromethane / 16 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 52, # 17 p. 2209 - 2211
反应条件
sodium hydroxide in chloroform; water 0.666667 h; microwave irradiation;
参考文献
Synthetic Communications, , vol. 36, # 17 p. 2421 - 2426
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride T=56°C;
参考文献
Chemische Berichte, , vol. 110, p. 96 - 106
