1-吡咯烷-1-环己烯合成路线 （共 146 条）
反应条件
in toluene 18 h; Molecular sieveDean-Stark trapHeating / reflux;
参考文献
GENKYO TEX
Patent: WO2008/116926 A1, 2008 ;
Location in patent: Page/Page column 48 ;
WO 2008/116926 A1
反应条件
2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; sodium t-butanolate; palladium diacetate in toluene T=80°C;
参考文献
Organic and Biomolecular Chemistry, , vol. 3, # 17 p. 3094 - 3095
反应条件
toluene-4-sulfonic acid in benzene 12 h; Heating;
参考文献
Seebach, Dieter; Beck, Albert K.; Badine, D. Michael; Limbach, Michael; Eschenmoser, Albert; Treasurywala, Adi M.; Hobi, Reinhard; Prikoszovich, Walter; Linder, Bernard
Helvetica Chimica Acta, 2007 , vol. 90, # 3 p. 425 - 471
反应条件
sodium methylate in methanol T=20°C; Elimination;
参考文献
Synthesis, , # 6 p. 1022 - 1026
参考文献
Journal of Organic Chemistry, , vol. 49, p. 1313 - 1314
反应条件
palladium diacetate; 1,2-bis-(diphenylphosphino)ethane 1.) THF, reflux, 2.) 100 degC, 2 h, water; Yield given. Multistep reaction;
参考文献
Lu, Xiyan; Huang, Yujin
Tetrahedron Letters, 1986 , vol. 27, # 14 p. 1615 - 1616
反应条件
1: 2) H2O / 1) dioxane, 120 deg C, 5 h, 2) dioxane, reflux, 1 h 2: 31.2 percent / LiAlH4 / diethyl ether / 4 h / Ambient temperature View Scheme
参考文献
Rejzek; Wimmer; Saman; Ricankova; Nemec
Helvetica Chimica Acta, 1994 , vol. 77, # 5 p. 1241 - 1255
反应条件
triethylamine; dichloro bis(acetonitrile) palladium(II) in acetonitrile T=20°C; 2 h;
参考文献
Ishikawa; Uedo; Tani; Saito
Journal of Organic Chemistry, 2001 , vol. 66, # 1 p. 186 - 191
反应条件
triethylamine in water; toluene 1.) toluene, reflux, 16 h, 2.) water, reflux, 1 h;
参考文献
Jones,R.A.; Stokes,M.J.
Tetrahedron, 1984 , vol. 40, p. 1051
反应条件
in acetonitrile T=25°C; Hydrolysis; trifluoromethylthiolation; 48 h;
参考文献
Synthetic Communications, , vol. 30, # 16 p. 2847 - 2854
