1-吡咯烷-1-环己烯合成路线 （共 146 条）
反应条件
1: 25 °C
2: HCl / methanol / 0 °C
View Scheme
参考文献
Law, Kam Wah; Lai, Ting-Fong; Sammes, Michael P.; Katritzky, Alan R.; Mak, Thomas C.W.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , p. 111 - 118
参考文献
Rao, T. Vedagiriswara; Anandan, Lalitha; Mathur, H. H.; Trivedi, G. K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 9 p. 864 - 867
反应条件
hydrogen; sodium iodide
1. EtOH; Yield given. Multistep reaction;
参考文献
Booth, Susan E.; Jenkins, Paul R.; Swain, Christopher J.; Sweeney, Joseph B.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 23 p. 3499 - 3508
反应条件
1: 2) H2O / 1) dioxane, 120 deg C, 5 h, 2) dioxane, reflux, 1 h
2: 31.2 percent / LiAlH4 / diethyl ether / 4 h / Ambient temperature
3: 1) 85percent H3PO4, 2) H2 / 2) Pd/CaCO3 / 1) 100 deg C, 4 h, 2) hexane, 12 h
4: BCl2H*Me2S / benzene / 24 h / Heating
View Scheme
参考文献
Rejzek; Wimmer; Saman; Ricankova; Nemec
Helvetica Chimica Acta, 1994 , vol. 77, # 5 p. 1241 - 1255
反应条件
1: 1-cyclohex-1-enylpyrrolidine; 1,2-dibromo-2-propene in 1,4-dioxane
Heating;
2: benzylamine in toluene
Heating;
参考文献
Tanyeli, Cihangir; Akhmedov, Idris M.; Yazicioglu, Emre Y.
Tetrahedron Letters, 2004 , vol. 45, # 52 p. 9627 - 9629
反应条件
1: With sodium iodide in acetone; acetonitrile
Stork alkylation; 24 h; Heating;
2: With water
Hydrolysis; 2 h; Heating;
参考文献
Stanetty, Peter; Bahardoust, M. Hassan; Mihovilovic, Marko D.; Mereiter, Kurt
Monatshefte fur Chemie, 1999 , vol. 130, # 10 p. 1257 - 1268
反应条件
benzoyl chloride in chloroform
12 h; Heating; Yield given;
参考文献
Klemm, L. H.; Muchiri, Daniel R.; Louris, John N.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 1135 - 1140
反应条件
1.1: triethylamine / dioxane / 6 h / Heating
1.2: 65 percent / HCl / 3 h / Heating
2.1: 31 percent / p-toluenesulfonic acid / toluene / 13 h / Heating
View Scheme
参考文献
Tanyeli, Cihangir; Akhmedov, Idris M.; Yazicioglu, Emre Y.
Tetrahedron Letters, 2004 , vol. 45, # 52 p. 9627 - 9629
反应条件
1: 7.6 g / dioxane / 12 h / Heating
2: 90 percent / potassium hydroxide / H2O / 4 h / 20 °C
View Scheme
参考文献
Muthusamy, Sengodagounder; Babu, Srinivasarao Arulananda; Gunanathan, Chidambaram; Suresh, Eringathodi; Dastidar, Parthasarathi
Bulletin of the Chemical Society of Japan, 2002 , vol. 75, # 4 p. 801 - 811
反应条件
1)dioxane, reflux, 2) water; Yield given. Multistep reaction;
参考文献
Kuchar, Miroslav; Brunova, Bohumila; Grimova, Jaroslava; Vanecek, Stanislav; Holubek, Jiri
Collection of Czechoslovak Chemical Communications, 1986 , vol. 51, # 12 p. 2896 - 2908
