1: 46 percent / diisopropylamine, n-butyllithium / tetrahydrofuran; hexane / -78 °C 2: 83 percent / 30percent hydrogen peroxide, acetic acid / H2O / 0.5 h View Scheme

1.1: sodium periodate; sodium hydroxide / water / 1 h / pH 5.5 / Inert atmosphere; Cooling with ice 1.2: 10 h / 20 °C / Inert atmosphere 2.1: hydrogenchloride / ethanol; water / 2.5 h / 20 °C / Inert atmosphere View Scheme

1.1: sulfuric acid / N,N-dimethyl-formamide / 8 h / 20 °C / pH 3 / Inert atmosphere; Cooling with ice 2.1: sodium periodate; sodium hydroxide / water / 1 h / pH 5.5 / Inert atmosphere; Cooling with ice 2.2: 10 h / 20 °C / Inert atmosphere 3.1: hydrogenchloride / ethanol; water / 2.5 h / 20 °C / Inert atmosphere View Scheme

1.1: palladium 10 on activated carbon; hydrogen / water / 50 °C / 2585.81 Torr 2.1: sulfuric acid / N,N-dimethyl-formamide / 8 h / 20 °C / pH 3 / Inert atmosphere; Cooling with ice 3.1: sodium periodate; sodium hydroxide / water / 1 h / pH 5.5 / Inert atmosphere; Cooling with ice 3.2: 10 h / 20 °C / Inert atmosphere 4.1: hydrogenchloride / ethanol; water / 2.5 h / 20 °C / Inert atmosphere View Scheme