3,17-二丙酸-17-BETA-雌二酯合成路线 （共 9 条）
参考文献
SOLVAY PHARMACEUTICALS GMBH
Patent: WO2006/125800 A1, 2006 ;
Location in patent: Page/Page column 88-89 ;
反应条件
1: 1.) 18.8percent aq. NaOH, 2.) NaBH4 / 1.) MeOH 2: 80.03 percent / pyridine / 1 h / 105 - 110 °C View Scheme
参考文献
Pharmaceutical Chemistry Journal, , vol. 17, # 9 p. 663 - 664
Khimiko-Farmatsevticheskii Zhurnal, , vol. 17, # 9 p. 1107 - 1108
反应条件
diethyl ether anschliessendes Kochen mit Propionsaeure-anhydrid;
反应条件
diethyl ether anschliessendes Kochen mit Propionsaeure-anhydrid;
参考文献
US2205627 , ;
DE685031 , ;
DRP/DRBP Org.Chem.
Helvetica Chimica Acta, , vol. 22, p. 250,252
Helvetica Chimica Acta, , vol. 20, p. 263,268
CH205434 , ;
反应条件
anschliessendes Kochen mit Propionsaeure-anhydrid;
反应条件
potassium carbonate in methanol 1.5 h; Ambient temperature;
参考文献
Shuvalova, S. D.; Men'shova, N. I.; Grinenko, G. S.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 9 p. 663 - 664
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 9 p. 1107 - 1108
参考文献
Miescher; Scholz
Helvetica Chimica Acta, 1937 , vol. 20, p. 263,268
Full Text Show Details
Ciba Pharm. Prod. Inc.
Patent: US2233025 , 1937 ;
Full Text Show Details
Ciba
Patent: CH213383 , 1937 ;
反应条件
1: 3,5-dimethyl-1H-pyrazole; chromium(VI) oxide / dichloromethane / -50 °C 2: methanol; sodium methylate / dichloromethane / 3.5 h / 20 °C View Scheme
参考文献
Gasi, Katarina Penov; Djurendic, Evgenija; Dojcinovic-Vujaskovic, Sanja; Gakovic, Andrea; Jovanovic-Santa, Suzana; Kojic, Vesna; Sakac, Marija
Chemical Papers, 2012 , vol. 66, # 4 p. 284 - 294
