3',4',5'-三甲氧基苯乙酮合成路线 （共 90 条）
反应条件
LiSEt in N,N-dimethyl-formamide T=70°C; 0.25 h; Inert atmosphereMicrowave irradiation; regioselective reaction;
参考文献
Cvengros, Jan; Neufeind, Stefan; Becker, Anne; Schmalz, Hans-Guenther
Synlett, 2008 , # 13 p. 1993 - 1998
反应条件
aluminium trichloride; chlorobenzene
参考文献
Mauthner
Journal fuer Praktische Chemie (Leipzig), 1927 , vol. <2> 115, p. 140
反应条件
iodine; magnesium in methanol T=20°C; 0.5 h;
参考文献
Khurana, Jitender M.; Bansal, Geeti; Kukreja, Gagan; Pandey, Ravi R.
Monatshefte fur Chemie, 2003 , vol. 134, # 10 p. 1365 - 1371
参考文献
Orion-yhtyma Oy
Patent: US4963590 A1, 1990 ;
US 4963590 A
反应条件
toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid in acetonitrile T=80°C; Baeyer-Villiger oxidation; 2 h; Further byproducts given;
参考文献
Bjorsvik, Hans-Rene; Occhipinti, Giovanni; Gambarotti, Cristian; Cerasino, Leonardo; Jensen, Vidar R.
Journal of Organic Chemistry, 2005 , vol. 70, # 18 p. 7290 - 7296
反应条件
dihydrogen peroxide; toluene-4-sulfonic acid; acetic acid T=80°C; Baeyer-Villiger oxidation; 1 h; Further byproducts given;
参考文献
Bjorsvik, Hans-Rene; Occhipinti, Giovanni; Gambarotti, Cristian; Cerasino, Leonardo; Jensen, Vidar R.
Journal of Organic Chemistry, 2005 , vol. 70, # 18 p. 7290 - 7296
反应条件
peracetic acid; perchloric acid; acetic anhydride in acetic acid
参考文献
Huee,R. et al.
Bulletin de la Societe Chimique de France, 1970 , p. 3617 - 3624
反应条件
sodium hydride in toluene; mineral oil
参考文献
Chen, Yi-Fong; Lin, Yi-Chien; Huang, Po-Kai; Chan, Hsu-Chin; Kuo, Sheng-Chu; Lee, Kuo-Hsiung; Huang, Li-Jiau
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 17 p. 5064 - 5075
反应条件
selenium(IV) oxide in 1,4-dioxane
参考文献
El-Mahdy, Ahmed F. M.; Shibata, Takayuki; Kabashima, Tsutomu; Kai, Masaaki
Chemical Communications, 2014 , vol. 50, # 7 p. 859 - 861
反应条件
1: With titanium(IV) isopropylate; ammonia in ethanol T=20°C; 6 h; Inert atmosphere; 2: With sodium tetrahydroborate in ethanol T=0 - 20°C; 3: With ammonia in ethanol; water
参考文献
NOVOTYR THERAPEUTICS LTD.
Patent: WO2009/147682 A1, 2009 ;
Location in patent: Page/Page column 59-60 ;
WO 2009/147682 A1
