4-甲氧基苯基磷酸二乙酯合成路线 （共 39 条）
反应条件
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; N-ethyl-N,N-diisopropylamine; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in tetrahydrofuran 4 h; RefluxInert atmosphere;
参考文献
Laven, Gaston; Kalek, Marcin; Jezowska, Martina; Stawinski, Jacek
New Journal of Chemistry, 2010 , vol. 34, # 5 p. 967 - 975
反应条件
T=130°C; Michaelis-Arbuzov rearrangement; 24 h;
参考文献
Murias, Marek; Handler, Norbert; Erker, Thomas; Pleban, Karin; Ecker, Gerhard; Saiko, Philipp; Szekeres, Thomas; Jaeger, Walter
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 21 p. 5571 - 5578
参考文献
Fresneda, P.M.; Molina, P.
Synthesis, 1981 , # 3 p. 222 - 223
参考文献
Synthesis, , p. 712 - 714
反应条件
1: 2N HCl, NaNO2 / H2O / 1.) -10 deg C, 10 min, 2.) 0 deg C, 20 min, 3.) 70 deg C 2: 1.) Na / 1.) ethanol, 2.) DMF, RT, 3.) H2O View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 22, p. 473 - 478
反应条件
1: methanol / 0.5 h / 20 °C 2: copper(l) iodide; caesium carbonate / ethylene glycol dimethyl ether / 2 h / 80 °C / |Inert atmosphere View Scheme
参考文献
Advanced Synthesis and Catalysis, , vol. 354, # 14-15 p. 2659 - 2664
参考文献
Berrier, C.; Jacquesy, J. C.; Gesson, J. P.; Renoux, A.
Tetrahedron, 1984 , vol. 40, # 11 p. 1983 - 1994
反应条件
1: 4-methoxy-toluene With N-bromosuccinmide; 2,2'-azo-bisisobutyronitrile in tetrachloromethane UV-irradiation; 2: triethyl phosphite Heating;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 19, # 1 p. 339 - 351
反应条件
1: 94.4 percent / LiAlH4 / diethyl ether / 4 h / Heating 2: 93.8 percent / SOCl2 / diethyl ether / 3 h / 20 °C 3: 4 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 53, # 12 p. 1587 - 1590
反应条件
1: 95.3 percent / K2CO3 / acetone / 3 h / Heating 2: 94.4 percent / LiAlH4 / diethyl ether / 4 h / Heating 3: 93.8 percent / SOCl2 / diethyl ether / 3 h / 20 °C 4: 4 h / Heating View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 53, # 12 p. 1587 - 1590
