1,3,3-三甲基吲哚啉-6’-(1-哌啶基)螺吩恶嗪合成路线 （共 7 条）
反应条件
1: 1-nitroso-2-hydroxy-naphthalene With zinc(II) chloride in tetrahydrofuran; water
T=20°C; 0.333333 h;
2: piperidine in ethanol
Michael addition; 2 h; Reflux;
3: 1,3-dihydro-1,3,3-trimethyl-2-methyleneindoline With sodium sulfate in ethanol
20 h; RefluxInert atmosphere;
参考文献
Pang, Mei-Li; Zhang, Hui-Juan; Liu, Pei-Pei; Zou, Zhi-Hong; Han, Jie; Meng, Ji-Ben
Synthesis, 2010 , # 20 art. no. F08010SS, p. 3418 - 3422
反应条件
dimethyl sulfoxide; triethylamine in methanol
T=40°C; 20 h;
参考文献
Koshkin; Lokshin; Samat; Gromov; Fedorova
Synthesis, 2005 , # 11 art. no. Z21004SS, p. 1876 - 1880
反应条件
1: NaOH / 20 °C
2: trichloroethene / 3.5 h / Heating
View Scheme
参考文献
Tan, Ting-Feng; Chen, Pei-Li; Huang, Hua-Ming; Meng, Ji-Ben
Tetrahedron, 2005 , vol. 61, # 34 p. 8192 - 8198
反应条件
1: 55 percent / H2O / Ambient temperature
2: 8 percent / NH2OH*HCl / ethanol / Ambient temperature
3: 30 percent / dioxane / Heating
View Scheme
参考文献
Rickwood; Marsden; Ormsby; Staunton; Wood; Hepworth; Gabbutt
Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 1994 , vol. 246, p. 17 - 24
反应条件
in 1,4-dioxane
Heating;
参考文献
Rickwood; Marsden; Ormsby; Staunton; Wood; Hepworth; Gabbutt
Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 1994 , vol. 246, p. 17 - 24
反应条件
1: 55 percent / H2O / Ambient temperature
2: 8 percent / NH2OH*HCl / ethanol / Ambient temperature
3: 30 percent / dioxane / Heating
View Scheme
参考文献
Rickwood; Marsden; Ormsby; Staunton; Wood; Hepworth; Gabbutt
Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, 1994 , vol. 246, p. 17 - 24
反应条件
1: trichloroethene / 0.5 h / Heating
2: trichloroethene / 3.5 h / Heating
View Scheme
参考文献
Tan, Ting-Feng; Chen, Pei-Li; Huang, Hua-Ming; Meng, Ji-Ben
Tetrahedron, 2005 , vol. 61, # 34 p. 8192 - 8198
