6-苄氧基萘-2-羧酸甲酯合成路线 （共 12 条）
反应条件
potassium carbonate in DMF (N,N-dimethyl-formamide) T=20°C; 16 h;
参考文献
DR. REDDY'S LABORATORIES LTD.
Patent: WO2005/40102 A2, 2005 ;
Location in patent: Page/Page column 46 ;
WO 2005/040102 A2
反应条件
4-(N,N-dimethlyamino)pyridine; dicyclohexyl-carbodiimide in dichloromethane 5 h; Ambient temperature;
参考文献
Jullien, Ludovic; Canceill, Josette; Valeur, Bernard; Bardez, Elisabeth; Lefevre, Jean-Pierre; Lehn, Jean-Marie; Marchi-Artzner, Valerie; Pansu, Robert
Journal of the American Chemical Society, 1996 , vol. 118, # 23 p. 5432 - 5442
反应条件
sulfuric acid in methanol
参考文献
SECRETARY OF STATE FOR DEFENCE, IN HER BRITANNIC MAJESTY'S GOV., OF THE UNITED KINGDOM OF, GREAT BRITAIN AND NORTHERN IRELAND
Patent: EP302875 B1, 1991 ;
反应条件
1: 75 percent / NaH / dimethylformamide / 22 h / 70 °C 2: 61 percent / dimethylformamide / 24 h / 150 °C 3: 67 percent / NaOH / 2-methoxy-ethanol / 8 h / Heating 4: 81 percent / DCC, DMAP / CH2Cl2 / 5 h / Ambient temperature View Scheme
参考文献
Jullien, Ludovic; Canceill, Josette; Valeur, Bernard; Bardez, Elisabeth; Lefevre, Jean-Pierre; Lehn, Jean-Marie; Marchi-Artzner, Valerie; Pansu, Robert
Journal of the American Chemical Society, 1996 , vol. 118, # 23 p. 5432 - 5442
反应条件
1: 61 percent / dimethylformamide / 24 h / 150 °C 2: 67 percent / NaOH / 2-methoxy-ethanol / 8 h / Heating 3: 81 percent / DCC, DMAP / CH2Cl2 / 5 h / Ambient temperature View Scheme
参考文献
Jullien, Ludovic; Canceill, Josette; Valeur, Bernard; Bardez, Elisabeth; Lefevre, Jean-Pierre; Lehn, Jean-Marie; Marchi-Artzner, Valerie; Pansu, Robert
Journal of the American Chemical Society, 1996 , vol. 118, # 23 p. 5432 - 5442
反应条件
1: 67 percent / NaOH / 2-methoxy-ethanol / 8 h / Heating 2: 81 percent / DCC, DMAP / CH2Cl2 / 5 h / Ambient temperature View Scheme
参考文献
Jullien, Ludovic; Canceill, Josette; Valeur, Bernard; Bardez, Elisabeth; Lefevre, Jean-Pierre; Lehn, Jean-Marie; Marchi-Artzner, Valerie; Pansu, Robert
Journal of the American Chemical Society, 1996 , vol. 118, # 23 p. 5432 - 5442
反应条件
1: 75 percent / NaH / dimethylformamide / 22 h / 70 °C 2: 61 percent / dimethylformamide / 24 h / 150 °C 3: 67 percent / NaOH / 2-methoxy-ethanol / 8 h / Heating 4: 81 percent / DCC, DMAP / CH2Cl2 / 5 h / Ambient temperature View Scheme
参考文献
Jullien, Ludovic; Canceill, Josette; Valeur, Bernard; Bardez, Elisabeth; Lefevre, Jean-Pierre; Lehn, Jean-Marie; Marchi-Artzner, Valerie; Pansu, Robert
Journal of the American Chemical Society, 1996 , vol. 118, # 23 p. 5432 - 5442
参考文献
The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland
Patent: US5061399 A1, 1991 ;
反应条件
hydrogen; palladium on activated charcoal in methanol 24 h; Ambient temperature;
参考文献
Jullien, Ludovic; Canceill, Josette; Valeur, Bernard; Bardez, Elisabeth; Lefevre, Jean-Pierre; Lehn, Jean-Marie; Marchi-Artzner, Valerie; Pansu, Robert
Journal of the American Chemical Society, 1996 , vol. 118, # 23 p. 5432 - 5442
反应条件
1: in tetrahydrofuran; water
Inert atmosphereAlkaline conditions;
2: With hydrogenchloride in tetrahydrofuran; water
pH=Ca. 1 - 3; Inert atmosphere;
参考文献
Deberardinis, Albert M.; Madden, Daniel J.; Banerjee, Upasana; Sail, Vibhavari; Raccuia, Daniel S.; De Carlo, Daniel; Lemieux, Steven M.; Meares, Adam; Hadden, M. Kyle
Journal of Medicinal Chemistry, 2014 , vol. 57, # 9 p. 3724 - 3736
