2-甲基-3-丁炔-2-醇合成路线 （共 621 条）
参考文献
Sacharowa
Zhurnal Obshchei Khimii, 1941 , vol. 11, p. 939,945
Chem.Abstr., 1943 , p. 355
反应条件
triethylamine; triphenylphosphine; palladium diacetate Substitution;
参考文献
Yamada, Koji; Imahori, Hiroshi; Nishimura, Yoshinobu; Yamazaki, Iwao; Sakata, Yoshiteru
Chemistry Letters, 1999 , # 9 p. 895 - 896
反应条件
C20H29Cl2N5O2Pd; potassium carbonate in ethanol T=80°C; Sonogashira Cross-Coupling; 2 h;
参考文献
Savicheva, Elizaveta A.; Kurandina, Daria V.; Nikiforov, Vladimir A.; Boyarskiy, Vadim P.
Tetrahedron Letters, 2014 , vol. 55, # 13 p. 2101 - 2103
反应条件
copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran T=40°C; 3 h;
参考文献
Tripier, Raphael; Hollenstein, Marcel; Elhabiri, Mourad; Chauvin, Anne-Sophie; Zucchi, Gael; Piguet, Claude; Buenzli, Jean-Claude G.
Helvetica Chimica Acta, 2002 , vol. 85, # 7 p. 1915 - 1929
反应条件
1: zinc-chloride-hydroxide 2: aqueous methanol. KOH-solution; nitrogen View Scheme
参考文献
Nickl
Chemische Berichte, 1958 , vol. 91, p. 1372,1375
参考文献
Mesplie, Yolande; Bergon, Michel; Calmon, Jean-Pierre
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 985 - 993
反应条件
bis-triphenylphosphine-palladium(II) chloride; triethylamine; copper(l) chloride T=80°C;
参考文献
Baranov, Denis S.; Ryabichev, Aleksey A.; Mamatyuk, Victor I.; Gatilov, Yurii V.; Kartsev, Victor G.; Vasilevsky, Sergei F.
Mendeleev Communications, 2012 , vol. 22, # 2 p. 114 - 116
反应条件
copper(l) iodide; triethylamine; triphenylphosphine T=90°C; Sonogashira coupling; 3 h; Inert atmosphere;
参考文献
Lin, Bo-Nan; Huang, Shao-Hsien; Wu, Wei-Yi; Mou, Chung-Yuan; Tsai, Fu-Yu
Molecules, 2010 , vol. 15, # 12 p. 9157 - 9173
反应条件
1: iodobenzene; 2-methyl-but-3-yn-2-ol With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisopropylamine T=50°C; 1 h; Inert atmosphere; 2: 1-(iodo)-4-methylbenzene With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium hydroxide T=110°C; 5 h; Inert atmosphere;
参考文献
Zhao, Yankai; Liu, Qiang; Li, Jing; Liu, Zhongquan; Zhou, Bo
Synlett, 2010 , # 12 p. 1870 - 1872
反应条件
diisopropylamine; copper(I) bromide in 1,4-dioxane 2.5 h; Heating;
参考文献
Searles, Scott; Li, Yushun; Nassim, Bahman; Lopes, Maria-Teresa Robert; Tran, P. T.; Crabbe, Pierre
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , # 4 p. 747 - 751
