2-甲基-3-丁炔-2-醇合成路线 （共 621 条）
反应条件
1,3-bis(tert-butyl)-imidazolium-2-carboxylate
T=50°C; P=760.051 Torr; Inert atmosphere;
参考文献
Kayaki, Yoshihito; Yamamoto, Masafumi; Ikariya, Takao
Angewandte Chemie, International Edition, 2009 , vol. 48, # 23 p. 4194 - 4197
反应条件
copper(l) chloride; [bmim][BS]
T=120°C; P=7600 Torr; 8 h;
参考文献
Gu, Yanlong; Shi, Feng; Deng, Youquan
Journal of Organic Chemistry, 2004 , vol. 69, # 2 p. 391 - 394
反应条件
carbon dioxide; tetraethylammonium chloride; silver(I) acetate; triphenylphosphine
参考文献
Roche Vitamins Inc.
Patent: US5817838 A1, 1998 ;
反应条件
1,3,4,6,7,8-hexahydro-1-methyl-2H-pyrimido{1,2-a}pyrimidine in acetonitile
T=100°C; P=33003.3 Torr; 24 h; Autoclave;
参考文献
Ca', Nicola Della; Gabriele, Bartolo; Ruffolo, Giuseppe; Veltri, Lucia; Zanetta, Tito; Costa, Mirco
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 1 p. 133 - 146
反应条件
1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine
T=100°C; P=7500.75 Torr; 24 h; Autoclave;
参考文献
Ca', Nicola Della; Gabriele, Bartolo; Ruffolo, Giuseppe; Veltri, Lucia; Zanetta, Tito; Costa, Mirco
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 1 p. 133 - 146
反应条件
1,3,4,6,7,8-hexahydro-1-methyl-2H-pyrimido{1,2-a}pyrimidine
T=100°C; P=7500.75 Torr; 24 h; Autoclave;
参考文献
Ca', Nicola Della; Gabriele, Bartolo; Ruffolo, Giuseppe; Veltri, Lucia; Zanetta, Tito; Costa, Mirco
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 1 p. 133 - 146
反应条件
copper(l) iodide in water
T=30°C; 72 h;
参考文献
Bieber, Lothar W.; Da Silva, Margarete F.
Tetrahedron Letters, 2004 , vol. 45, # 45 p. 8281 - 8283
反应条件
piperidine; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) in diethyl ether
T=20°C;
参考文献
Alami, Mouad; Peyrat, Jean-Francois; Brion, Jean-Daniel
Tetrahedron Letters, 2002 , vol. 43, # 16 p. 3007 - 3009
反应条件
piperidine; copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride in diethyl ether
T=20°C; 4 h;
参考文献
Hamze, Abdallah; Provot, Olivier; Brion, Jean-Daniel; Alami, Mouad
Journal of Organic Chemistry, 2007 , vol. 72, # 10 p. 3868 - 3874
反应条件
1: Py
2: H2 / PtO2
View Scheme
参考文献
Boisselle,A.P.; Meinhardt,N.A.
Journal of Organic Chemistry, 1962 , vol. 27, p. 1828 - 1833
