N-CBZ-L-天冬氨酸合成路线 （共 76 条）
反应条件
1: 90 percent / Et3N / acetonitrile / 2 h / 5 °C 2: 85 percent / Et3N / H2O / Ambient temperature View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 62, # 10 p. 3103 - 3108
参考文献
Tetrahedron Asymmetry, , vol. 18, # 13 p. 1625 - 1627
反应条件
thermolysin T=25°C; Rate constant;
参考文献
Tetrahedron, , vol. 48, # 6 p. 1115 - 1122
反应条件
1: toluene / anfangs unter Kuehlung 2: MgO; water; diethyl ether View Scheme
参考文献
Chemische Berichte, , vol. 65, p. 1192,1198
反应条件
resolved on CSP cellulose tris(3,5-dimethylphenylcarbamate) by chiral HPLC;
参考文献
Chemistry Letters, , p. 1125 - 1128
反应条件
triethylamine in dichloromethane T=0°C; 1 h; Yield given. Title compound not separated from byproducts;
参考文献
Jouin, P.; Castro, B.; Zeggaf, C.; Pantaloni, A.; Senet, J.P; et al
Tetrahedron Letters, 1987 , vol. 28, # 15 p. 1665 - 1668
反应条件
triethylamine in dichloromethane T=0°C; 1 h; Yields of byproduct given;
参考文献
Jouin, P.; Castro, B.; Zeggaf, C.; Pantaloni, A.; Senet, J.P; et al
Tetrahedron Letters, 1987 , vol. 28, # 15 p. 1665 - 1668
反应条件
1: toluene 2: aqueous dioxane; aqueous NaOH View Scheme
参考文献
DeTar; Rogers Jr.; Bach
Journal of the American Chemical Society, 1967 , vol. 89, # 12 p. 3039 - 3045
反应条件
4-(N,N-dimethlyamino)pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane T=0 - 20°C; 20 h; Title compound not separated from byproducts.;
参考文献
Burtin, Guillaume; Corringer, Pierre-Jean; Young, Douglas W.
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 20 p. 3451 - 3459
反应条件
sulfuric acid T=20°C; 5.5 h; Product distribution / selectivity;
参考文献
Allen, David Robert; Kyung-Lee, Seung-Hee
Patent: US2003/236430 A1, 2003 ;
Location in patent: Page 3 ;
