反应条件
1: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C
2: hydrogenchloride; tetrafluoroboric acid; sodium nitrite / water
3: dichloromethane; boron tribromide / 0 - 20 °C
4: tripotassium phosphate / water; toluene / 0 - 20 °C
5: 1,1'-bis-(diphenylphosphino)ferrocene; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 80 °C
6: hydrogenchloride; sodium periodate / tetrahydrofuran; water
8: TMS halide / acetonitrile / 20 °C
View Scheme
参考文献
Jin, Jian; Morales-Ramos, Angel; Eidam, Patrick; Mecom, John; Li, Yue; Brooks, Carl; Hilfiker, Mark; Zhang, David; Wang, Ning; Shi, Dongchuan; Tseng, Pei-San; Wheless, Karen; Budzik, Brian; Evans, Karen; Jaworski, Jon-Paul; Jugus, Jack; Leon, Lisa; Wu, Charlene; Pullen, Mark; Karamshi, Bhumika; Rao, Parvathi; Ward, Emma; Laping, Nicholas; Evans, Christopher; Leach, Colin; Holt, Dennis; Su, Xin; Morrow, Dwight; Fries, Harvey; Thorneloe, Kevin; Edwards, Richard
ACS Medicinal Chemistry Letters, 2010 , vol. 1, # 7 p. 316 - 320