乙基3-环己基-2-氟-3-氧代丙酸酯合成路线 （共 7 条）
反应条件
water; silica gel in ethyl acetate T=20°C; dephosphonylation; 16 h;
参考文献
Kim, Dae Young
Synthetic Communications, 2000 , vol. 30, # 7 p. 1205 - 1212
反应条件
Dess-Martin periodane in dichloromethane 3 h; Ambient temperature;
参考文献
Linderman, Russell J.; Graves, David M.
Journal of Organic Chemistry, 1989 , vol. 54, # 3 p. 661 - 668
反应条件
Et3N-5HF; 1-(iodo)-4-methylbenzene electrolysis: smooth Pt sheets as the anode and the cathode, undivided cell, 1.5 V (vs. Ag/Ag(+)), 10.0 F/mol;
参考文献
Hara, Shoji; Hatakeyama, Tsuyoshi; Chen, Sheng-Qi; Ishi-I, Kenji; Yoshida, Masanori; Sawaguchi, Masanori; Fukuhara, Tsuyoshi; Yoneda, Norihiko
Journal of Fluorine Chemistry, 1998 , vol. 87, # 2 p. 189 - 192
反应条件
1: 58 percent / acivated zinc dust / tetrahydrofuran / 0.17 h / Heating 2: 87 percent / Dess-Martin periodinane / CH2Cl2 / 3 h / Ambient temperature View Scheme
参考文献
Linderman, Russell J.; Graves, David M.
Journal of Organic Chemistry, 1989 , vol. 54, # 3 p. 661 - 668
反应条件
1: boron trifluoride diethyl etherate / dichloromethane / 1.5 h / 20 °C / |Inert atmosphere 2: HBF4*Et2O / dichloromethane / 5 h / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
Pasceri, Raffaele; Bartrum, Hannah E.; Hayes, Christopher J.; Moody, Christopher J.
Chemical Communications, 2012 , vol. 48, # 99 p. 12077 - 12079
反应条件
1: 4-Acetylaminobenzenesulfonyl Azide; triethylamine / acetonitrile / 16 h / 0 - 20 °C / |Inert atmosphere; |Enzymatic reaction 2: HBF4*Et2O / dichloromethane / 5 h / 0 - 20 °C / |Inert atmosphere View Scheme
参考文献
Pasceri, Raffaele; Bartrum, Hannah E.; Hayes, Christopher J.; Moody, Christopher J.
Chemical Communications, 2012 , vol. 48, # 99 p. 12077 - 12079
反应条件
Yield given. Multistep reaction;
参考文献
Thenappan, Alagappan; Burton, Donald J.
Journal of Organic Chemistry, 1991 , vol. 56, # 1 p. 273 - 277
