三羟甲基氨基甲烷盐酸盐合成路线

参考文献

Yoshida, Kitaro; Yano, Kazuyuki; Nagamatsu, Kazuo
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1985 , p. 437 - 442

1185-53-1三羟甲基氨基甲烷盐酸盐

6000-43-7甘氨酸盐酸盐

参考文献

ATHENA DISCOVERY, INC.
Patent: US2011/243942 A1, 2011 ;

1185-53-1三羟甲基氨基甲烷盐酸盐+

77-76-92,2-二甲氧基丙烷

74181-34-32,2-二甲基-1,3-二恶烷-5-酮

参考文献

Cagide-Fagin, Fernando; Alonso, Ricardo
European Journal of Organic Chemistry, 2010 , # 35 p. 6741 - 6747

1185-53-1三羟甲基氨基甲烷盐酸盐+

77-76-92,2-二甲氧基丙烷

53104-32-85-氨基-2,2-二甲基-1,3-二恶烷-5-甲醇

参考文献

Forbes, David C.; Ene, Doina G.; Doyle, Michael P.
Synthesis, 1998 , # 6 p. 879 - 882

56-45-1L-丝氨酸+

303-38-82,3-二羟基苯甲酸+

1185-53-1三羟甲基氨基甲烷盐酸盐

参考文献

Guo, Zu-Feng; Jiang, Ming; Zheng, Suilan; Guo, Zhihong
Organic Letters, 2008 , vol. 10, # 4 p. 649 - 652

56-45-1L-丝氨酸+

303-38-82,3-二羟基苯甲酸+

1185-53-1三羟甲基氨基甲烷盐酸盐

参考文献

Guo, Zu-Feng; Jiang, Ming; Zheng, Suilan; Guo, Zhihong
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 13 p. 3855 - 3858

1125-88-8苯甲醛二甲缩醛+

1185-53-1三羟甲基氨基甲烷盐酸盐

51430-74-1

参考文献

Forbes, David C.; Ene, Doina G.; Doyle, Michael P.
Synthesis, 1998 , # 6 p. 879 - 882