(4-甲基苯基)(3-噻吩基)甲酮合成路线 （共 3 条）
反应条件
1: thiophen-3-yl boronic acid; 1-(iodo)-4-methylbenzene With potassium carbonate in toluene Suzuki Coupling; 0.166667 h; Autoclave; 2: carbon monoxide in toluene T=100°C; P=7500.75 Torr; 10 h;
参考文献
Khedkar, Mayur V.; Sasaki, Takehiko; Bhanage, Bhalchandra M.
RSC Advances, 2013 , vol. 3, # 21 p. 7791 - 7797
反应条件
hydrogenchloride; n-butyllithium; water Yield given. Multistep reaction;
参考文献
Merck and Co., Inc.
Patent: EP268396 A1, 1988 ;
反应条件
1: With 3,3-dimethyl-butan-2-one T=20°C; Oppenauer Oxidation; 3 h; Cooling with ice; 2: With trifluoroacetic acid T=20°C; 48 h;
参考文献
Fu, Ying; Yang, Yanshou; Huegel, Helmut M.; Du, Zhengyin; Wang, Kehu; Huang, Danfeng; Hu, Yulai
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 27 p. 4429 - 4432
