1: 53 percent / various solvent(s) / 3 h / Heating
2: 22 percent / K2CO3 / dimethylformamide / 3 h / Heating
View Scheme
参考文献
Bender, Paul E.; Hill, David T.; Offen, Priscilla H.; Razgaitis, Kazys; Lavanchy, Patricia; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 9 p. 1169 - 1177
1: aqueous phosphoric acid / 100 - 120 °C / Destillieren des Reaktionsprodukts bei 0.1 Torr bzw. bei 0.2 Torr
2: LiAlH4 / anschliessendes Erhitzen mit wss. H3PO4
View Scheme
参考文献
Sumrell; Goheen
Journal of the American Chemical Society, 1955 , vol. 77, p. 3805
1: trichloromonobromomethane With triphenylphosphine in dichloromethane
T=20°C; Appel reaction; 0.666667 h; in air;
2: 4,4'-bismethoxybenzoin in dichloromethane
T=20°C; Appel reaction; in air;
参考文献
Newman, Stephen G.; Bryan, Christopher S.; Perez, Didier; Lautens, Mark
Synthesis, 2011 , # 2 art. no. Z27210SS, p. 342 - 346