5-氯甲基-3-甲基-1,2,4-噁二唑合成路线 （共 3 条）
参考文献
Chevron Research Company
Patent: US4237121 A1, 1980 ;
反应条件
1: phosphonic acid diethyl ester With lithium hexamethyldisilazane in tetrahydrofuran
T=-10°C; 0.333333 h; Inert atmosphere;
2: 3-methyl-1,2,4-oxadiazol-5-ylmethyl chloride in tetrahydrofuran
T=-10 - 20°C;
参考文献
RECORDATI IRELAND LIMITED; LEONARDI, Amedeo; MOTTA, Gianni; RIVA, Carlo; GUARNERI, Luciano; GRAZIANI, Davide; MARINONI, Fabio; BETTINELLI, Ilaria
Patent: WO2011/29633 A1, 2011 ;
Location in patent: Page/Page column 62 ;
WO 2011/029633 A1
参考文献
Franke,A. et al.
Synthesis, 1979 , p. 712 - 714
