2-甲氧基-4,4,5,5-四甲基-1,3,2-二氧硼戊环合成路线 （共 52 条）
反应条件
1: 1,4-dibromo-2-fluorobenzene With n-butyllithium in diethyl ether; hexane T=-80°C; 0.5 h; Inert atmosphere; 2: MeOB(pin) in tetrahydrofuran; diethyl ether; hexane T=-70°C; 0.5 h; Inert atmosphere; Further stages;
参考文献
Kurach, Pawel; Lulinski, Sergiusz; Serwatowski, Janusz
European Journal of Organic Chemistry, 2008 , # 18 p. 3171 - 3178
反应条件
1: 1,3-diiodobenzene With isopropylmagnesium chloride lithium chloride complex in tetrahydrofuran T=-20°C; 1 h; 2: MeOB(pin) in tetrahydrofuran T=-20 - 20°C;
参考文献
Baron, Oliver; Knochel, Paul
Angewandte Chemie - International Edition, 2005 , vol. 44, # 20 p. 3133 - 3135
反应条件
1: 3,5-dibromo-1-fluorobenzene With n-butyllithium in diethyl ether; hexane T=-80°C; 0.5 h; Inert atmosphere; 2: MeOB(pin) in tetrahydrofuran; diethyl ether; hexane T=-70°C; 0.5 h; Inert atmosphere; 3: carbon dioxide Further stages;
参考文献
Kurach, Pawel; Lulinski, Sergiusz; Serwatowski, Janusz
European Journal of Organic Chemistry, 2008 , # 18 p. 3171 - 3178
反应条件
1: 4-methoxy-ortho-bromophenol With n-butyllithium in tetrahydrofuran T=-78 - 0°C; 1.25 h; Inert atmosphere; 2: MeOB(pin) in tetrahydrofuran T=0 - 20°C; Inert atmosphere;
参考文献
Friedman, Adam A.; Panteleev, Jane; Tsoung, Jennifer; Huynh, Vaizanne; Lautens, Mark
Angewandte Chemie - International Edition, 2013 , vol. 52, # 37 p. 9755 - 9758
反应条件
CH3CH2CH2CH2Li in tetrahydrofuran treatment of pyrrole deriv. with butyllithium in THF at -78°C, addn. of borolane deriv.;
参考文献
Ayats, Carles; Soley, Roger; Albericio, Fernando; Alvarez, Mercedes
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 5 p. 860 - 862
反应条件
1: 1,2-diiodobenzene With isopropylmagnesium chloride lithium chloride complex in tetrahydrofuran T=-78°C; 3 h; 2: MeOB(pin) in tetrahydrofuran T=-78 - 20°C;
参考文献
Baron, Oliver; Knochel, Paul
Angewandte Chemie - International Edition, 2005 , vol. 44, # 20 p. 3133 - 3135
反应条件
1: tert-butyl 4-(4-iodo-1H-pyrazol-1-yl)piperidine-1-carboxylate With isopropylmagnesium chloride in tetrahydrofuran T=-10 - 0°C; 5.25 h; Large scale reaction; 2: MeOB(pin) in tetrahydrofuran T=20 - 25°C; 10.75 h; Large scale reaction;
参考文献
De Koning, Pieter D.; McAndrew, Douglas; Moore, Robert; Moses, Ian B.; Boyles, David C.; Kissick, Kyle; Stanchina, Corey L.; Cuthbertson, Timothy; Kamatani, Asayuki; Rahman, Leera; Rodriguez, Rick; Urbina, Armando; Sandovalnee Accacia, Alison; Rose, Peter R.
Organic Process Research and Development, 2011 , vol. 15, # 5 p. 1018 - 1026
反应条件
1: tert-butyl 4-(4-bromo-1H-pyrazol-1-yl)piperidine-1-carboxylate With isopropylmagnesium chloride; lithium chloride in tetrahydrofuran T=20 - 30°C; 12 h; 2: MeOB(pin) in tetrahydrofuran T=20 - 30°C; 6 h;
参考文献
Qian, Jian-Qiang; Yan, Pu-Cha; Che, Da-Qing; Zhou, Qi-Lin; Li, Yuan-Qiang
Tetrahedron Letters, 2014 , vol. 55, # 9 p. 1528 - 1531
反应条件
1: 1-chlorocyclopentene With lithium in diethyl ether T=20°C; 2: MeOB(pin) in diethyl ether T=20°C; Cooling with acetone-dry ice;
参考文献
UNIVERSAL DISPLAY CORPORATION; MA, Bin; DEANGELIS, Alan; XIA, Chuanjun; ADAMOVICH, Vadim
Patent: WO2012/148511 A1, 2012 ;
Location in patent: Page/Page column 62-63 ;
反应条件
1: 1,4-Diiodobenzene With isopropylmagnesium chloride lithium chloride complex in tetrahydrofuran T=-20°C; 1 h; 2: MeOB(pin) in tetrahydrofuran T=-20 - 20°C;
参考文献
Baron, Oliver; Knochel, Paul
Angewandte Chemie - International Edition, 2005 , vol. 44, # 20 p. 3133 - 3135
