1: 93 percent / NaI / acetone / 48 h / Heating 2: 1.) n-BuLi / 1.) THF, hexan, -80 deg C, 2.) DMSO, RT View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '19257410', constants.ctx, '0')">Amberlyst H-15</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730733', constants.ctx, '0')">hexane</a> <br />&nbsp;Ambient temperature;&nbsp;&nbsp;Yield given;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 95 percent / Amberlyst H-15 / hexane / 8 h / Ambient temperature<br />2: 1.) Mg, 2.) CuCN, LiCl / 1.) Et₂O, reflux, 2.) THF, 0 deg C, 1 h<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '4948473', constants.ctx, '0')">magnesium</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '8127934', constants.ctx, '0')">lithium chloride</a> <br />&nbsp;1.) Et₂O, reflux, 2.) THF, 0 deg C, 1 h;&nbsp;&nbsp;Yield given. Multistep reaction;&nbsp;<br /> &nbsp;