3-氰基-1H-吡唑-4-羧酸乙酯合成路线 （共 7 条）
反应条件
sodium carbonate; trichlorophosphate in acetonitrile 1.5 h; Heating;
参考文献
Tao, E. V. P.; Aikins, J.; Rizzo, J.; Beck, J. R.; Lynch, M. P.
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 1293 - 1294
反应条件
1: conc. ammonium hydroxide / ethyl acetate / 16 h / Ambient temperature 2: phosphorus oxychloride, potassium carbonate / acetonitrile / 3.5 h / Heating View Scheme
参考文献
Tao, E. V. P.; Rizzo, John R.; Aikins, James
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 6 p. 1655 - 1656
反应条件
1: sodium nitrite / ethyl acetate; H2O / Ambient temperature 2: conc. ammonium hydroxide / ethyl acetate / 16 h / Ambient temperature 3: phosphorus oxychloride, potassium carbonate / acetonitrile / 3.5 h / Heating View Scheme
参考文献
Tao, E. V. P.; Rizzo, John R.; Aikins, James
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 6 p. 1655 - 1656
反应条件
1: sodium nitrite / ethyl acetate; H2O / Ambient temperature 2: conc. ammonium hydroxide / ethyl acetate / 16 h / Ambient temperature 3: phosphorus oxychloride, potassium carbonate / acetonitrile / 3.5 h / Heating View Scheme
参考文献
Tao, E. V. P.; Rizzo, John R.; Aikins, James
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 6 p. 1655 - 1656
反应条件
toluene-4-sulfonic acid in acetonitrile
16 h; Heating;
参考文献
Tao, E. V. P.; Rizzo, John R.; Aikins, James
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 6 p. 1655 - 1656
参考文献
Babbitt, George E.; Lynch, Michael P.; Beck, James R.
Magnetic Resonance in Chemistry, 1990 , vol. 28, # 1 p. 90 - 92
反应条件
toluene-4-sulfonic acid in acetonitrile
18 h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Tao, E. V. P.; Aikins, J.; Rizzo, J.; Beck, J. R.; Lynch, M. P.
Journal of Heterocyclic Chemistry, 1988 , vol. 25, p. 1293 - 1294
