6-溴-1,1,4,4,7-五甲基-1,2,3,4-四氢萘合成路线 （共 14 条）
反应条件
1: 2,5-dimethyl-2,5-dihydroxy hexane With hydrogenchloride in water; toluene T=20°C; 2: toluene With AlCl3, aluminium chloride T=60°C; 2 h; 3: With hydrogen bromide; dihydrogen peroxide; propionic acid in water T=50 - 80°C; 3 h;
参考文献
US2007/232810 A1, ;
Page/Page column 6-7 ;
反应条件
aluminium trichloride; bromine in dichloromethane
参考文献
Journal of Organic Chemistry, , vol. 66, # 17 p. 5772 - 5782
反应条件
1: 99 percent / AlCl3 / CH2Cl2 / 20 °C 2: 85 percent / Br2; AlCl3 / CH2Cl2 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 17 p. 5772 - 5782
反应条件
aluminium trichloride
参考文献
Tetrahedron Letters, , vol. 38, # 46 p. 8067 - 8070
反应条件
aluminium chloride in methanol
反应条件
1: 61 percent / H2 / 5percent Pd/C / ethanol; dioxane / 20 h / 1292.9 - 1551.4 Torr / Ambient temperature 2: 26 percent / hexyl nitrite, CHBr3 / 1.5 h / 95 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 7 p. 1504 - 1517
反应条件
1-Hexyl nitrite; tribromo methane T=95°C; 1.5 h;
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 7 p. 1504 - 1517
反应条件
1: HCl conc. / 3 h / 20 °C 2: 99 percent / AlCl3 / CH2Cl2 / 20 °C 3: 85 percent / Br2; AlCl3 / CH2Cl2 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 66, # 17 p. 5772 - 5782
反应条件
n-butyllithium in tetrahydrofuran
参考文献
Lapierre, Jean-Marc; Rotstein, David Mark; Sjogren, Eric Brian
Patent: US2002/82265 A1, 2002 ;
参考文献
C.I.R.D. Galderma
Patent: US5716624 A1, 1998 ;
