3,4-二甲氧基苯甲醛合成路线 （共 996 条）
反应条件
mit einem Ueberschuss;
参考文献
Behal; Tiffeneau
Bulletin de la Societe Chimique de France, 1908 , vol. <4> 3, p. 316
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1905 , vol. 141, p. 597
反应条件
1: (i) Py, (ii) aq. HCl 2: H2 / Raney-Ni / ethanol / 100 °C / 66195.7 Torr 3: H3PO4, P2O5 View Scheme
参考文献
Fillion, Eric; Fishlock, Dan; Wilsily, Ashraf; Goll, Julie M.
Journal of Organic Chemistry, 2005 , vol. 70, # 4 p. 1316 - 1327
反应条件
2: 89 percent / pyridine / Ambient temperature 3: 83 percent / NaH / dimethylformamide 4: 75 percent / KOH / ethanol; H2O / Heating View Scheme
参考文献
Badia, D.; Dominguez, E.; Galarza, J.; Lete, E.; Marigorta, E. Martinez de; Villa, M. J.
Bulletin des Societes Chimiques Belges, 1989 , vol. 98, # 1 p. 77 - 82
反应条件
1.1: (n-Bu)2BOTf; Et3N / CH2Cl2 / 1.33 h / -78 - 0 °C 1.2: CH2Cl2 / 2 h / -78 - 0 °C 1.3: H2O2 / CH2Cl2; aq. phosphate buffer / 20 °C / pH 7.2 2.1: 1.45 g / 2,6-lutidine / CH2Cl2 / 1 h / 20 °C 3.1: 85 percent / NaBH4 / tetrahydrofuran; H2O / 16 h / 25 °C 4.1: 88 percent / pyridine / CH2Cl2 / 1 h / 20 °C 5.1: 44 percent / (Me3Si)3SiH; AIBN / benzene / 4 h / Heating 6.1: 86 percent / AcOH; (n-Bu)4NF / tetrahydrofuran / 336 h / 20 °C 7.1: 80 percent / H2; HClO4 / Pd/C / ethanol / 48 h / 3040 Torr View Scheme
参考文献
Fischer, Joshua; Reynolds, Aaron J.; Sharp, Lisa A.; Sherburn, Michael S.
Organic Letters, 2004 , vol. 6, # 9 p. 1345 - 1348
反应条件
toluene-4-sulfonic acid; triphenylphosphine 15 h; Heating;
参考文献
Wang, Min; Gao, Mingzhang; Mock, Bruce H.; Miller, Kathy D.; Sledge, George W.; Hutchins, Gary D.; Zheng, Qi-Huang
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 24 p. 8599 - 8607
反应条件
1,10-phenanthroline; CuCl2·2H2O; potassium carbonate; sulfur in water T=100°C; 24 h;
参考文献
Deng, Hang; Li, Zhengkai; Ke, Fang; Zhou, Xiangge
Chemistry - A European Journal, 2012 , vol. 18, # 16 p. 4840 - 4843
反应条件
formic acid; sodium sulfate; triethylamine in methanol; chloroform; Petroleum ether
参考文献
BIOGAL GYOGYSZERGYAR
Patent: EP578850 A1, 1994 ;
反应条件
1: sodium 2: amalgamated aluminium; diethyl ether View Scheme
参考文献
Kindler; Peschke
Archiv der Pharmazie (Weinheim, Germany), 1932 , vol. 270, p. 353,359
反应条件
chloroform; chlorine T=40 - 50°C;
参考文献
Squier; Van der Schyf; Oliver; Venter
Arzneimittel-Forschung/Drug Research, 1986 , vol. 36, # 3 p. 457 - 460
参考文献
Ginsburg
Journal of the American Chemical Society, 1951 , vol. 73, p. 702
