3,4-二甲氧基苯甲醛合成路线 （共 996 条）
参考文献
Pschorr
Justus Liebigs Annalen der Chemie, 1912 , vol. 391, p. 44
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Piccinini
Chem. Zentralbl., 1905 , vol. 76, # II p. 623
反应条件
1: piperidine / 72 h / 30 - 40 °C 2: KOH / ethanol / Heating 3: polyphosphoric acid / Heating View Scheme
参考文献
Pramanik; Mukherjee
Journal of the Indian Chemical Society, 1997 , vol. 74, # 9 p. 734 - 735
反应条件
1: 1.) LDA / 1.) THF, -70 deg C, 10 min, 2.) THF, -70 deg C, 30 min 2: trifluoroacetic acid / CH2Cl2 / Ambient temperature 3: 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / benzene / 8 h / Heating 4: lithium aluminum hydride / tetrahydrofuran / 1.) from -20 deg C to 10 deg C, 1 h, 2.) 10 deg C, 1 h View Scheme
参考文献
Iwasaki, Tameo; Kondo, Kazuhiko; Kuroda, Tooru; Moritani, Yasunori; Yamagata, Shinsuke; Sugiura, Masaki; Kikkawa, Hideo; Kaminuma, Osamu; Ikezawa, Katsuo
Journal of Medicinal Chemistry, 1996 , vol. 39, # 14 p. 2696 - 2704
反应条件
in ethanol 2 h; Reflux;
参考文献
Riedel, Franziska; Spange, Stefan
Journal of Physical Organic Chemistry, 2012 , vol. 25, # 12 p. 1261 - 1268
反应条件
1: ammonium acetate / 3 h / Heating 2: LiAlH4 / tetrahydrofuran / 4 h / Ambient temperature 3: benzene / Heating 4: NaBH4 / ethanol / 0.5 h / Ambient temperature 5: K2CO3 / Ambient temperature 6: trifluoroacetic acid / 1 h / Ambient temperature View Scheme
参考文献
Kubo, Akinori; Saito, Naoki; Kawakami, Nanko; Matsuyama, Yasuo; Miwa, Teruyo
Synthesis, 1987 , # 9 p. 824 - 827
参考文献
Klayman; Bartosevich; Griffin; Mason; Scovill
Journal of Medicinal Chemistry, 1979 , vol. 22, # 7 p. 855 - 862
反应条件
1: 99 percent / KOH / ethanol / 3 h / 20 °C 2: 90 percent / BBr3 / CH2Cl2 / 0.5 h / 0 °C 3: 65 percent / dimethyl dioxirane / acetone; CH2Cl2 / 1 h / 0 - 20 °C 4: 95 percent / K2CO3 / acetone / 6 h / Heating 5: 71 percent / I2; pyridine / 8 h / Heating 6: 94 percent / BBr3 / CH2Cl2 / 0.5 h / 0 °C 7: 90 percent / dimethyl dioxirane / acetone; CH2Cl2 / 0.33 h / 0 - 20 °C 8: 87 percent / K2CO3 / acetone; CH2Cl2 / 6 h / Heating 9: 80 percent / dimethyl dioxirane / acetone; CH2Cl2 / 0.17 h / 0 - 20 °C View Scheme
参考文献
Tetrahedron, , vol. 60, # 11 p. 2647 - 2655
反应条件
hydrogenchloride in ethanol 0.5 h; Heating;
参考文献
Christinaki, Helene; Bister-Miel, Francoise; Hammoumi, Abderahmane; Bury, Michele; Guignard, Jean-Louis; Viel, Claude
Phytochemistry (Elsevier), 1987 , vol. 26, # 11 p. 2991 - 2994
反应条件
2: NaBH4 3: 31 percent / HCl / ethanol / 0.5 h / Heating View Scheme
参考文献
Christinaki, Helene; Bister-Miel, Francoise; Hammoumi, Abderahmane; Bury, Michele; Guignard, Jean-Louis; Viel, Claude
Phytochemistry (Elsevier), 1987 , vol. 26, # 11 p. 2991 - 2994
反应条件
2: platinum; acetic acid / Hydrogenation View Scheme
参考文献
Buck
Journal of the American Chemical Society, 1931 , vol. 53, p. 2192,2195,2198
