3,4-二甲氧基苯乙胺合成路线 （共 365 条）
反应条件
in chloroform
T=0 - 5°C; 3 h;
参考文献
Lee, Chai-Ho; Oh, Jung Mee; Lee, Jong-Dae; Nakamura, Hiroyukiki; Ko, Jaejung; Kang, Sang Ook
Synlett, 2006 , # 2 p. 275 - 278
反应条件
1: toluene / 3 h / Heating
2: trifluoroacetic acid / 1.5 h / Heating
3: 1.5 h / Heating
View Scheme
参考文献
Youn, So Won
Journal of Organic Chemistry, 2006 , vol. 71, # 6 p. 2521 - 2523
反应条件
1: toluene / Heating
2: trifluoroacetic acid / Heating
3: CH2Cl2
View Scheme
参考文献
Youn, So Won
Journal of Organic Chemistry, 2006 , vol. 71, # 6 p. 2521 - 2523
反应条件
1: toluene / Heating
2: trifluoroacetic acid / Heating
3: CH2Cl2
View Scheme
参考文献
Gitto, Rosaria; Barreca, Maria Letizia; De Luca, Laura; De Sarro, Giovambattista; Ferreri, Guido; Quartarone, Silvana; Russo, Emilio; Constanti, Andrew; Chimirri, Alba
Journal of Medicinal Chemistry, 2003 , vol. 46, # 1 p. 197 - 200
反应条件
sodium hydroxide in dichloromethane; water
T=0 - 20°C; Schotten-Baumann Reaction; 3 h;
参考文献
Parraga, Javier; Cabedo, Nuria; Andujar, Sebastian; Piqueras, Laura; Moreno, Laura; Galan, Abraham; Angelina, Emilio; Enriz, Ricardo D.; Ivorra, Maria Dolores; Sanz, Maria Jesus; Cortes, Diego
European Journal of Medicinal Chemistry, 2013 , vol. 68, p. 150 - 166
反应条件
1: (3-methoxy-phenyl)-acetic acid With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane
T=20°C; 0.5 h;
2: 2-(3,4-dimethoxyphenyl)-ethylamine in dichloromethane
T=20°C; 8 h;
参考文献
Qian, Wangke; Lu, Weijian; Sun, Haifeng; Li, Zeng; Zhu, Liyuan; Zhao, Rui; Zhang, Lei; Zhou, Shengbin; Zhou, Yu; Jiang, Hualiang; Zhen, Xuechu; Liu, Hong
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 15 p. 4862 - 4871
反应条件
sodium hydroxide in diethyl ether
Ambient temperature;
参考文献
Minor, Deborah L.; Wyrick, Steven D.; Charifson, Paul S.; Watts, Val J.; Nichols, David E.; Mailman, Richard B.
Journal of Medicinal Chemistry, 1994 , vol. 37, # 25 p. 4317 - 4328
反应条件
tetra-(n-butyl)ammonium iodide in dichloromethane
Ambient temperatureelectrolyzed at -1.7 V at 50 mA;
参考文献
Arai, Kenji; Shaw, Chu-hei; Nozawa, Koohei; Kawai, Ken-ichi; Nakajima, Shoichi
Tetrahedron Letters, 1987 , vol. 28, # 4 p. 441 - 442
反应条件
1: With potassium phosphate; sodium iodide in sulfolane
T=20 - 35°C; Inert atmosphere;
2: With tert.-butylhydroperoxide in sulfolane; decane
T=30 - 35°C; Inert atmosphere;
参考文献
Shankar; More, Satish S.; Madhubabu; Vembu; Syam Kumar
Synlett, 2012 , vol. 23, # 7 p. 1013 - 1020
反应条件
silica gel; toluene-4-sulfonic acid
0.0333333 h; microwave irradiation;
参考文献
Hajipour; Ghasemi
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2001 , vol. 40, # 6 p. 504 - 507
