环戊并[c]吡咯-1-羧酸,八氢-盐酸盐合成路线 (共 3 条)
反应条件
hydrogenchloride; water in methanol 24 h; Reflux;
参考文献
US2014/94616 A1, ;
Paragraph 0147-0150 ;
反应条件
hydrogenchloride; water 24 h; Reflux;
参考文献
WO2010/8828 A2, ;
Page/Page column 96 ;
反应条件
1: acetic acid tert-butyl ester; (1S,3aR,6aS)-octahydrocyclopenta[c]pyrrole-1-carboxylic acid hydrochloride With methanesulfonic acid in chloroform T=0 - 25°C; 18 h; 2: oxalic acid in isopropyl alcohol T=75 - 80°C; 0.5 h;
参考文献
SUMITOMO CHEMICAL COMPANY, LIMITED; Ikemoto, Tetsuya; Lutete, Leopold Mpaka; Aikawa, Toshiaki
Patent: US2014/94616 A1, 2014 ;
Location in patent: Paragraph 0155 ;