(E)-3-[2-(7-氯-2-喹啉基)乙烯基]苯甲醛合成路线 （共 17 条）
反应条件
in tetrahydrofuran; toluene T=0 - 5°C; 1 h; Yields of byproduct given;
参考文献
King; Corley; Anderson; Larsen; Verhoeven; Reider
Journal of Organic Chemistry, 1993 , vol. 58, # 14 p. 3731 - 3735
反应条件
1: 92 percent / toluene; tetrahydrofuran / 1 h / 0 - 5 °C 2: 83 percent / Et3N / Pd(OAc)2 / acetonitrile / 12 h / Heating 3: 87.1 percent / (+)-α-pinene, chloroborane-methyl sulfide, diisopropylethylamine / hexane; tetrahydrofuran / 1) -20 deg C, 3.5 h, 2) to 0 deg C, 1 h View Scheme
参考文献
King; Corley; Anderson; Larsen; Verhoeven; Reider
Journal of Organic Chemistry, 1993 , vol. 58, # 14 p. 3731 - 3735
反应条件
1: in tetrahydrofuran T=-10 - 5°C; 2.75 h; 2: With water T=10 - 15°C; 0.5 h;
参考文献
MOREPEN LABORATORIES LIMITED
Patent: WO2006/21974 A1, 2006 ;
Location in patent: Page/Page column 20 ;
反应条件
1: 92 percent / toluene; tetrahydrofuran / 1 h / 0 - 5 °C 2: 83 percent / Et3N / Pd(OAc)2 / acetonitrile / 12 h / Heating View Scheme
参考文献
King; Corley; Anderson; Larsen; Verhoeven; Reider
Journal of Organic Chemistry, 1993 , vol. 58, # 14 p. 3731 - 3735
反应条件
in methanol; hexane; ethyl acetate; trifluoroacetic acid; trifluoroacetic anhydride
参考文献
Merck Frosst Canada, Inc.
Patent: US5104882 A1, 1992 ;
反应条件
boron trifluoride diethyl etherate in dichloromethane T=-5 - 0°C; 2 h;
参考文献
McNamara, J. M.; Leazer, J. L.; Bhupathy, M.; Amato, J. S.; Reamer, R. A.; et al.
Journal of Organic Chemistry, 1989 , vol. 54, # 15 p. 3718 - 3721
反应条件
MeMgBr in tetrahydrofuran
参考文献
Merck Frosst Canada, Inc.
Patent: US5104882 A1, 1992 ;
