3-氨基-4-氯三氟甲苯合成路线 （共 32 条）
参考文献
Zhao, Yan-Fang; Liu, Zi-Jian; Zhai, Xin; Ge, Dan-Dan; Huang, Qiang; Gong, Ping
Chinese Chemical Letters, 2013 , vol. 24, # 5 p. 386 - 388
反应条件
1: 1) HCl, NaNO2; 2) CH3COONa*3H2O, CuSO4*5H2O, Na2SO3 / 1) H2O, 0-5 deg C; 2) 2 h, 10-20 deg C; 3) aq. HCl 2: 99 percent / NaBH4 / dioxane; H2O / 0.5 h / 30 - 40 °C 3: 86 percent / SOCl2 / CHCl3; pyridine / 48 h / 10 - 20 °C View Scheme
参考文献
Sindelar; Holubek; Ryska; et al.
Collection of Czechoslovak Chemical Communications, 1982 , vol. 47, # 3 p. 967 - 983
反应条件
1: 1-amino-2-chloro-5-trifluoromethylbenzene With hydrogenchloride; sodium nitrite T=0 - 5°C; 2: furan-2-carboxylic acid With copper dichloride in water T=20°C; 4 h; Further stages.;
参考文献
Prasad, D. Jagadeesh; Karthikeyan; Karegoudar, Prakash B.; Poojary, Boja; Holla, B. Shivarama; Kumari, N. Suchetha
Phosphorus, Sulfur and Silicon and the Related Elements, 2007 , vol. 182, # 5 p. 1083 - 1091
反应条件
hydrogenchloride; sodium acetate; copper(II) sulfate; sodium sulfite; sodium nitrite 1) H2O, 0-5 deg C; 2) 2 h, 10-20 deg C; 3) aq. HCl; Yield given. Multistep reaction;
参考文献
Collection of Czechoslovak Chemical Communications, , vol. 47, # 3 p. 967 - 983
反应条件
(i) NaNO2, aq. HCl, (ii) SO3, CuCl2, AcOH; Multistep reaction;
参考文献
Gandel'sman,L.Z. et al.
Sov. Prog. Chem. (Engl. Transl.), 1975 , vol. 41, # 1 p. 61 - 66,57 - 61
反应条件
(i) H2SO4, (ii) aq. NaNO2, (iii) aq. KI; Multistep reaction;
参考文献
Loev,B.
Canadian Journal of Chemistry, 1964 , vol. 42, p. 1488 - 1490
反应条件
1: (i) NaNO2, H2SO4, (ii) aq. ZnCl2, (iii) /BRN= 3587243/, CuCN, aq. NaHCO3, PE 2: aq. NaOH / Heating 3: SOCl2 / Heating View Scheme
参考文献
Saucy,G.; Sternbach,L.H.
Helvetica Chimica Acta, 1962 , vol. 45, p. 2226 - 2241
反应条件
1: 1) HCl, NaNO2; 2) CH3COONa*3H2O, CuSO4*5H2O, Na2SO3 / 1) H2O, 0-5 deg C; 2) 2 h, 10-20 deg C; 3) aq. HCl 2: 99 percent / NaBH4 / dioxane; H2O / 0.5 h / 30 - 40 °C View Scheme
参考文献
Sindelar; Holubek; Ryska; et al.
Collection of Czechoslovak Chemical Communications, 1982 , vol. 47, # 3 p. 967 - 983
反应条件
1: (i) H2SO4, (ii) aq. NaNO2, (iii) aq. KI 2: (i) Mg, BrCH2CH2Br, Et2O, (ii) /BRN= 1900390/ View Scheme
参考文献
Saucy,G.; Sternbach,L.H.
Helvetica Chimica Acta, 1962 , vol. 45, p. 2226 - 2241
参考文献
Ankodia, Vandana; Sharma, Praveen Kumar; Sharma, Kailash; Kumar; Gupta, Archana
Heterocyclic Communications, 2009 , vol. 15, # 2 p. 127 - 133
