1: With sodium t-butanolate in toluene T=20°C; 0.5 h; 2: With tris-(dibenzylideneacetone)dipalladium(0); 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in toluene T=100°C; 16 h;
参考文献
ENCYSIVE PHARMACEUTICALS INC.
Patent: WO2009/44311 A1, 2009 ;
Location in patent: Page/Page column 39 ;
WO 2009/044311 A1