反应条件
1: 1.) diisopropylamine, BuLi / 1.) THF, hexane, a) -50 deg C, 15 min, b) RT, 1 h, 2.) -78 deg C, 3 h 2: H2 / 10percent Pd/C / tetrahydrofuran / 760 Torr / Ambient temperature 3: p-TsOH, / CHCl3 / Ambient temperature 4: Jones' reagent / acetone / 1 h / 10 °C 5: 84 percent / H2 / PtO2 / ethyl acetate / 48 h / 37503 Torr / Ambient temperature View Scheme
参考文献
Barbier, Pierre; Schneider, Fernand
Journal of Organic Chemistry, 1988 , vol. 53, # 6 p. 1218 - 1221
